Seifert Posy J, Morgan Renee C, Conover David L, Arieno Andrea L
Elizabeth Wende Breast Care, LLC, Rochester, NY, USA.
Radiation Safety Unit, University of Rochester, Rochester, NY, USA.
J Clin Imaging Sci. 2017 Jan 27;7:1. doi: 10.4103/2156-7514.199055. eCollection 2017.
To evaluate our initial experience with a cone-beam breast computed tomography (BCT)-guided breast biopsy system for lesion retrieval in phantom studies for use with a cone-beam BCT imaging system.
Under the Institutional Review Board approval, a phantom biopsy study was performed using a dedicated BCT-guided biopsy system. Fifteen biopsies were performed on each of the small, medium, and large anthropomorphic breast phantoms with both BCT and stereotactic guidance for comparison. Each set of the 45 phantoms contained masses and calcification clusters of varying sizes. Data included mass/calcium retrieval rate and dose and length of procedure time for phantom studies.
Phantom mass and calcium retrieval rate were 100% for BCT and stereotactic biopsy. BCT dose for small and medium breast phantoms was found to be equivalent to or less than the corresponding stereotactic approach. Stereotactic-guided biopsy dose was 34.2 and 62.5 mGy for small and medium breast phantoms, respectively. BCT-guided biopsy dose was 15.4 and 30.0 mGy for small and medium breast phantoms, respectively. Both computed tomography biopsy and stereotactic biopsy study time ranged from 10 to 20 min.
Initial experience with a BCT-guided biopsy system has shown to be comparable to stereotactic biopsy in phantom studies with equivalent or decreased dose.
评估我们在体模研究中使用锥形束乳腺计算机断层扫描（BCT）引导下的乳腺活检系统进行病变取出的初步经验，该系统用于与锥形束BCT成像系统配合使用。
在机构审查委员会批准下，使用专用的BCT引导活检系统进行了体模活检研究。对小型、中型和大型拟人化乳腺体模分别进行了15次活检，同时采用BCT和立体定向引导进行比较。每组45个体模包含不同大小的肿块和钙化簇。数据包括体模研究中的肿块/钙取出率、剂量以及操作时间长度。
BCT和立体定向活检的体模肿块和钙取出率均为100%。发现小型和中型乳腺体模的BCT剂量等于或低于相应的立体定向方法。小型和中型乳腺体模的立体定向引导活检剂量分别为34.2和62.5 mGy。小型和中型乳腺体模的BCT引导活检剂量分别为15.4和30.0 mGy。计算机断层扫描活检和立体定向活检的研究时间均为10至20分钟。
在体模研究中，BCT引导活检系统的初步经验表明，其在剂量相当或降低的情况下，与立体定向活检相当。
