Doassans S, Osman H, Joujoux J M, Guillot B
Service de Dermatologie, CHU de Nîmes.
Ann Dermatol Venereol. 1994;121(10):724-6.
There are many skin manifestations of Crohn's disease including specific lesions occurring late after digestive signs. These manifestations are also termed metastatic and are rarely located on the vulva.
We observed a metastatic localization in the vulva of Crohn's disease in a 34-year-old woman with predominantly rectosigmoid disease. The right labia major was greatly enlarged with oedema involving the inguinal cural area. Pustulization and erosive lesions were seen. The course of these lesions was independent of the colonic disease and responded temporarily only to a triple drug combination of metronidazol, prednisolone and minocyclin.
This case emphasizes the frequency of colonic or rectal manifestations associated with vulval involvement in Crohn's disease. The metastatic lesions follow a course independent of the digestive disease raising therapeutic problems in this localization.
克罗恩病有许多皮肤表现，包括在消化症状出现很久之后出现的特异性病变。这些表现也被称为转移性病变，很少发生在外阴。
我们观察到一名34岁主要患有直肠乙状结肠疾病的女性克罗恩病在外阴出现转移性病变。右侧大阴唇明显肿大，水肿累及腹股沟区。可见脓疱和糜烂性病变。这些病变的病程与结肠疾病无关，仅对甲硝唑、泼尼松龙和米诺环素三联药物组合暂时有反应。
该病例强调了克罗恩病中外阴受累相关的结肠或直肠表现的发生率。转移性病变的病程与消化系统疾病无关，这给该部位的治疗带来了问题。
