Wall Michael, Woodward Kimberly R, Doyle Carrie K, Zamba Gideon
Department of Neurology, College of Medicine, Veterans Administration Hospital, University of Iowa, Iowa City, IA 52242-1053, USA.
Arch Ophthalmol. 2010 May;128(5):570-6. doi: 10.1001/archophthalmol.2010.71.
To establish the associations between threshold estimates of 4 perimetric tests and to define and compare the tests' effective dynamic ranges.
We examined 152 patients with glaucoma and 80 controls using standard automated perimetry (SAP) with stimulus size III, SAP with size V, and motion and matrix perimetry. We explored the intertest associations using principal-components analysis. We defined the effective dynamic range bottom using the frequency of 0-dB trials on retest. We defined the upper effective dynamic range as a value above which fewer than 0.5% of the values fall in the controls. We also calculated the number of discriminable steps from normal to the floor value of the perimeter.
The association between SAP III and V was approximately linear up to a sensitivity of about 20 dB on both tests and with motion and matrix perimetry up to about 25 dB from 0 dB. While the upper bounds were similar among the tests, size V SAP had a lower floor and more discriminable steps.
The effective dynamic range of SAP III is substantially less than its physically tested limits. Size V stimuli have a greater effective dynamic range than size III by about 1 log unit and have about twice as many discriminable steps.
建立4种视野检查阈值估计值之间的关联,并定义和比较这些检查的有效动态范围。
我们使用刺激大小为III的标准自动视野计(SAP)、刺激大小为V的SAP以及运动和矩阵视野计对152例青光眼患者和80例对照者进行了检查。我们使用主成分分析探索了不同检查之间的关联。我们根据复测时0 dB试验的频率定义了有效动态范围下限。我们将有效动态范围上限定义为一个值,高于该值时对照组中低于该值的数值不到0.5%。我们还计算了从正常到视野计下限值的可辨别步数。
在两种检查中,SAP III和V之间的关联在敏感度约为20 dB之前大致呈线性,与运动和矩阵视野计在从0 dB起约25 dB之前也是如此。虽然不同检查的上限相似,但刺激大小为V的SAP下限较低且可辨别步数更多。
SAP III的有效动态范围远小于其实际测试极限。刺激大小为V的刺激比刺激大小为III的刺激有效动态范围大约大1个对数单位,且可辨别步数约为其两倍。