Jarrett O, Hardy W D, Golder M C, Hay D
Int J Cancer. 1978 Mar 15;21(3):334-7. doi: 10.1002/ijc.2910210314.
Feline leukaemia viruses (FeLV) were isolated from cats in Glasgow and New York with lymphosarcoma and from apparently healthy carrier cats. The subgroup composition of each isolate was determined. All isolates contained FeLV of subgroup A(FeLV-A) and a high proportion also contained subgroup B virus (FeLV-B). Virus of subgroup C (FeLV-C) was rare and occurred in association with FeLV-A and, in some isolates, with FeLV-B as well. The same pattern was observed in isolates from British and American cats. The frequency of FeLV subgroups was different in cats with lymphosarcoma and in healthy carrier cats. In cats with lymphosarcoma, 42% had FeLV-A and 58% had FeLV-AB; there was no obvious correlation between virus subgroup and type of disease. In FeLV-positive healthy cats, 65% had FeLV-A and 33% had FeLV-AB. FeLV-C was isolated only from cats with disease. The healthy carrier cats were from multiple-cat households (MCH). Two distinct types of FeLV-infected MCH were found: MCH-A in which the carrier cats yielded only FeLV-A, and MCH-AB in which cats with either FeLV-A or FeLV-AB were present. In MCH-AB half of the cats had FeLV-A and half had FeLV-AB. Overall, the proportion of cats in MCH which were viraemic with FeLV was 42%. However, there was a marked difference in the prevalence of carrier cats in each type of MCH: in MCH-A, 28% were FeLV-positive while in MCH-AB, 53% were viraemic.
猫白血病病毒（FeLV）是从格拉斯哥和纽约患有淋巴肉瘤的猫以及看似健康的带毒猫中分离出来的。确定了每个分离株的亚组组成。所有分离株都含有A亚组猫白血病病毒（FeLV-A），并且很大一部分还含有B亚组病毒（FeLV-B）。C亚组病毒（FeLV-C）很罕见，与FeLV-A一起出现，在一些分离株中也与FeLV-B一起出现。在从英国和美国猫分离出的毒株中观察到相同的模式。FeLV亚组在患有淋巴肉瘤的猫和健康带毒猫中的频率不同。在患有淋巴肉瘤的猫中，42%有FeLV-A，58%有FeLV-AB；病毒亚组与疾病类型之间没有明显的相关性。在FeLV阳性的健康猫中，65%有FeLV-A，33%有FeLV-AB。FeLV-C仅从患病猫中分离出来。健康带毒猫来自多猫家庭（MCH）。发现了两种不同类型的FeLV感染的MCH：MCH-A，其中带毒猫只产生FeLV-A；MCH-AB，其中存在有FeLV-A或FeLV-AB的猫。在MCH-AB中，一半的猫有FeLV-A，一半有FeLV-AB。总体而言，MCH中感染FeLV病毒血症的猫的比例为42%。然而，每种类型的MCH中带毒猫的患病率有显著差异：在MCH-A中，28%的猫FeLV呈阳性，而在MCH-AB中，53%的猫有病毒血症。
