Weijer K
Tijdschr Diergeneeskd. 1975 Sep 15;100(18):976-86.
Seven different groups of cats were examined to study the incidence and distribution of feline leukaemia virus (FeLV) in the Netherlands. The indirect fluorescent antibody (IFA) technique was used to detect FeLV antigen. Of the cats with lymphosarcoma (leukaemia), 73.2 per cent and of those with infectious peritonitis, 32.4 per cent were found to be positive for FeLV antigen. Of the sixty-six cats with other tumours, only one, a cat with carcinoma of the mammary gland; was positive for FeLV antigen. Of 557 cats with various lesions, forty-two (7.5 percent) were positive for FeLV antigen. The IFA-test was found to be a useful adjunct in establishing the correct diagnosis. Of all stud cats which had been in contact with FeLV-positive cats, 24.7 percent were positive for FeLV antigen, wheras all those which had not been in contact with these cats, were negative. There was a marked difference between the proportions of FeLV-positive cats in the groups of clinically normal cats which had (20.6 per cent) and which had not (0.4 per cent) been in contact with FeLV-positive cats. Follow-up studies showed that 67.8 percent of the clinically normal, FeLV-positive cats had died from or been sacrificed because of FeLV-associated diseases within twenty months.
为研究荷兰猫白血病病毒(FeLV)的发病率和分布情况,对七组不同的猫进行了检查。采用间接荧光抗体(IFA)技术检测FeLV抗原。在患有淋巴肉瘤(白血病)的猫中,73.2%检测出FeLV抗原呈阳性;在患有传染性腹膜炎的猫中,这一比例为32.4%。在66只患有其他肿瘤的猫中,只有一只患有乳腺腺癌的猫FeLV抗原呈阳性。在557只有各种病变的猫中,42只(7.5%)FeLV抗原呈阳性。IFA检测被发现是辅助正确诊断的有用方法。在所有与FeLV阳性猫接触过的种公猫中,24.7%的猫FeLV抗原呈阳性,而所有未与这些猫接触过的种公猫均为阴性。在曾接触过(20.6%)和未接触过(0.4%)FeLV阳性猫的临床正常猫组中,FeLV阳性猫的比例存在显著差异。随访研究表明,67.8%临床正常的FeLV阳性猫在20个月内死于FeLV相关疾病或因这类疾病而被安乐死。