Guglielmi G, Viñuela F, Dion J, Duckwiler G
Department of Neurological Sciences, University of Rome Medical School, Italy.
J Neurosurg. 1991 Jul;75(1):8-14. doi: 10.3171/jns.1991.75.1.0008.
Fifteen patients with high-risk intracranial saccular aneurysms were treated using electrolytically detachable coils introduced via an endovascular approach. The patients ranged in age from 21 to 69 years. The most frequent clinical presentation was subarachnoid hemorrhage (eight cases). Considerable thrombosis of the aneurysm (70% to 100%) was achieved in all 15 patients, and preservation of the parent artery was obtained in 14. Although temporary neurological deterioration due to the technique was recorded in one patient, no permanent neurological deficit was observed in this series and there were no deaths. It is believed that this new technology is a viable alternative in the management of patients with high-risk intracranial saccular aneurysms. It may also play an important role in the occlusion of aneurysms in the acute phase of subarachnoid hemorrhage.
采用血管内介入方法，通过电解可脱性弹簧圈治疗了15例高危颅内囊状动脉瘤患者。患者年龄在21岁至69岁之间。最常见的临床表现是蛛网膜下腔出血（8例）。15例患者的动脉瘤均实现了显著血栓形成（70%至100%），14例患者的载瘤动脉得以保留。尽管有1例患者记录到因该技术导致的暂时性神经功能恶化，但本系列中未观察到永久性神经功能缺损，也无死亡病例。据信，这项新技术是治疗高危颅内囊状动脉瘤患者的一种可行替代方法。它在蛛网膜下腔出血急性期动脉瘤的闭塞治疗中也可能发挥重要作用。
