Faculty of Medicine, Rouen University Hospital Ch. Nicolle, University of Rouen, Rouen, France.
World J Biol Psychiatry. 2010 Jun;11(4):604-55. doi: 10.3109/15622971003671628.
The primary aim of these guidelines was to evaluate the role of pharmacological agents in the treatment and management of paraphilia, with a focus on the treatment of adults males. Because such treatments are not delivered in isolation, the role of specific psychosocial and psychotherapeutic interventions was also briefly covered. These guidelines are intended for use in clinical practice by clinicians who diagnose and treat patients with paraphilia. The aim of these guidelines is to improve the quality of care and to aid physicians in clinical decisions.
The aim of these guidelines was to bring together different views on the appropriate treatment of paraphilias from experts representing different continents. To achieve this aim, an extensive literature search was conducted using the English language literature indexed on MEDLINE/PubMed (1990-2009 for SSRIs) (1969-2009 for antiandrogen treatments), supplemented by other sources, including published reviews.
Each treatment recommendation was evaluated and discussed with respect to the strength of evidence for its efficacy, safety, tolerability and feasibility.
An algorithm was proposed with six levels of treatment for different categories of paraphilias.
本指南的主要目的是评估药物治疗在治疗和管理性偏好障碍中的作用，重点关注成年男性的治疗。由于这些治疗并非孤立进行，因此也简要介绍了特定心理社会和心理治疗干预的作用。本指南旨在为诊断和治疗性偏好障碍患者的临床医生在临床实践中使用。本指南的目的是提高护理质量并帮助医生做出临床决策。
本指南旨在汇集来自代表不同大洲的专家对适当治疗性偏好障碍的不同观点。为了实现这一目标，使用 MEDLINE/PubMed 索引的英语文献进行了广泛的文献检索（SSRIs 为 1990-2009 年，抗雄激素治疗为 1969-2009 年），并辅以其他来源，包括已发表的综述。
针对每种治疗建议，都根据其疗效、安全性、耐受性和可行性的证据强度进行了评估和讨论。
针对不同类别的性偏好障碍提出了一个包含六个级别的治疗算法。
