Mangraviti Antonella, Mazzucchi Edoardo, Izzo Alessandro, Sturdà Cosimo, Albanese Alessio, Marchese Enrico, Olivi Alessandro, Puca Alfredo, Sturiale Carmelo Lucio
Institute of Neurosurgery, Fondazione Policlinico Universitario A. Gemelli - IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.
Institute of Neurosurgery, Fondazione Policlinico Universitario A. Gemelli - IRCCS, Rome, Italy.
Asian J Neurosurg. 2018 Oct-Dec;13(4):1288-1291. doi: 10.4103/ajns.AJNS_91_18.
Epidermoid cysts (ECs) are benign and slow-growing lesions that account for about 0.2%-2% of all intracranial tumors. Symptoms appear slowly and tumors may have already grown to giant proportions when patients receive their first diagnosis. The optimal treatment for ECs is surgical removal, which includes the total resection of the entire capsule of the lesion in order to minimize the risk of malignant transformation associated with partial removal. However, considering the giant size that the ECs can reach at the time of the diagnosis, and their adherence to the surrounding structures, the risks and benefits of total versus subtotal resections in the short- and long-term patients' outcome are still under debate. Here, we report a case of an extensive giant EC and offer a discussion of its characteristics, surgical management, and postoperative outcome, taking a cue to argue about the recent literature based in the latest case studies.
表皮样囊肿（ECs）是良性且生长缓慢的病变，约占所有颅内肿瘤的0.2%-2%。症状出现缓慢，当患者首次确诊时，肿瘤可能已经生长到巨大尺寸。ECs的最佳治疗方法是手术切除，包括完整切除病变的整个包膜，以尽量降低与部分切除相关的恶变风险。然而，考虑到ECs在诊断时可能达到的巨大尺寸，以及它们与周围结构的粘连，全切除与次全切除在短期和长期患者预后方面的风险和益处仍存在争议。在此，我们报告一例广泛的巨大EC病例，并对其特征、手术管理和术后结果进行讨论，同时结合最新的病例研究对近期文献进行探讨。
