Shulev Yury, Trashin Alexander, Gordienko Konstantin
Neurosurgical Department #1, City Hospital #2, Saint-Petersburg Medical Academy of Postgraduate Studies, Saint-Petersburg, Russia.
Skull Base. 2011 Sep;21(5):287-94. doi: 10.1055/s-0031-1284218.
The analysis of the treatment results in patients with cerebellopontine angle (CPA) tumors, manifested as trigeminal neuralgia (TN). During the 10-year period from 1998 to 2008, 14 patients with verified CPA tumors that had the typical manifestations of TN were operated on at our hospital (5.8% from all patients with TN who underwent surgery). In nine cases the epidermoid was identified; three patients had meningioma, one patient had acoustic neurinoma, and one patient had lipoma. The follow-up of all patients lasted at least 12 months. The intraoperative assessment identified the three variants of relationship between the tumors and neurovascular structures: (1) tumor grows around the trigeminal nerve; (2) the tumor causes compression and displacement of the trigeminal nerve; and (3) tumor presses the arterial vessel to the trigeminal nerve by moving the vessel or nerve. For six patients, with removal of tumor a microvascular decompression of the trigeminal nerve was performed. Complete pain relief was achieved in 12 patients (86%). TN is an expectative symptom of CPA tumors. The most frequent cause of secondary TN of CPA tumors is epidermoid. All patients with manifestations of TN should undergo the magnetic resonance imaging for early diagnosis of CPA tumor.
对表现为三叉神经痛(TN)的桥小脑角(CPA)肿瘤患者的治疗结果进行分析。在1998年至2008年的10年期间,我院对14例经证实患有具有典型TN表现的CPA肿瘤患者进行了手术(占所有接受手术的TN患者的5.8%)。其中9例为表皮样囊肿;3例为脑膜瘤,1例为听神经瘤,1例为脂肪瘤。所有患者的随访时间至少为12个月。术中评估确定了肿瘤与神经血管结构之间关系的三种变体:(1)肿瘤围绕三叉神经生长;(2)肿瘤导致三叉神经受压和移位;(3)肿瘤通过移动血管或神经将动脉血管压向三叉神经。对于6例患者,在切除肿瘤的同时对三叉神经进行了微血管减压。12例患者(86%)实现了完全疼痛缓解。TN是CPA肿瘤的一个预期症状。CPA肿瘤继发性TN最常见的原因是表皮样囊肿。所有有TN表现的患者都应进行磁共振成像检查,以便早期诊断CPA肿瘤。