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[用乙状结肠替代膀胱治疗膀胱癌]

[Bladder replacement with sigmoid colon for bladder cancer].

作者信息

Nishimura N, Suzu H, Yushita Y, Yamashita S, Kanetake H, Saito Y, Sakuragi T

机构信息

Department of Urology, Nagasaki University School of Medicine.

出版信息

Nihon Hinyokika Gakkai Zasshi. 1991 Jan;82(1):41-6. doi: 10.5980/jpnjurol1989.82.41.

Abstract

From 1972 to 1989, 21 patients underwent bladder replacement with sigmoid colon after cystectomy for bladder cancer. A portion of sigmoid colon (about 15 to 20 cm) was isolated and anastomosed to the urethral stump. Then the ureters were implanted in the sigmoid colon via submucosal tunnels. There were 20 men and 1 woman, ranging in age from 24 to 71 years (average 51 years). Preoperative investigations showed that all the cases were free of metastasis. Five years survival rate was 60.7% and there was no operative mortality. There was urethral recurrence in one case and in that case postoperative histopathology revealed carcinoma in situ with tumor. All patients were able to void by themselves without any difficulty. Five patients complained mild incontinence at daytime and all patients had mild incontinence during deep sleep at night, but all of them could maintain their normal daily life like before. The major postoperative complications were: leak at the site of anastomosis (between sigmoid colon and urethra) in 6 cases, hydronephrosis in 2 cases, VUR in 2 cases and bladder stone in 1 case. The patients who underwent bladder replacement with sigmoid colon were well satisfied, because there were no external stoma and the patients could void by themselves. From now, we want to improve our operative method in order to avoid postoperative incontinence.

摘要

1972年至1989年期间,21例膀胱癌患者在膀胱切除术后接受了乙状结肠膀胱替代术。截取一段乙状结肠(约15至20厘米),将其与尿道残端吻合。然后经黏膜下隧道将输尿管植入乙状结肠。患者中男性20例,女性1例,年龄在24至71岁之间(平均51岁)。术前检查显示所有病例均无转移。五年生存率为60.7%,无手术死亡病例。1例出现尿道复发,该病例术后组织病理学显示原位癌伴肿瘤。所有患者均能自行排尿,无任何困难。5例患者白天诉轻度尿失禁,所有患者夜间熟睡时均有轻度尿失禁,但均能像以前一样维持正常日常生活。术后主要并发症有:乙状结肠与尿道吻合口漏6例、肾积水2例、膀胱输尿管反流2例、膀胱结石1例。接受乙状结肠膀胱替代术的患者满意度较高,因为没有外置造口,患者能够自行排尿。从现在起,我们希望改进手术方法以避免术后尿失禁。

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