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无症状、无室性心律失常的年轻患者右心室心肌内脂肪沉积的发生率。

Prevalence of fat deposition within the right ventricular myocardium in asymptomatic young patients without ventricular arrhythmias.

机构信息

Department of Radiology, Mayo Clinic, Rochester, MN, USA.

出版信息

J Thorac Imaging. 2010 May;25(2):173-8. doi: 10.1097/RTI.0b013e3181b669d8.

DOI:10.1097/RTI.0b013e3181b669d8
PMID:20463537
Abstract

PURPOSE

Variable amounts of intramyocardial fat can be found within the right ventricular muscle fibers. We aimed to determine the prevalence of intramyocardial fat deposition within the right ventricle (RV) in asymptomatic patients aged 40 years and younger who underwent imaging of the heart for coronary artery disease screening.

MATERIALS AND METHODS

Retrospective review of 540 consecutive patients aged 40 years or younger referred for coronary calcium scoring.

RESULTS

The images were reviewed by 2 dedicated cardiac radiologists, and the following specific observations were made: presence or absence of macroscopic fat in the RV by location, RV size as normal or enlarged, and presence of additional foci of fat deposition in the visualized thorax. The clinical data were reviewed from the patients' medical record, and the following information was recorded: age, sex, body mass index, and the presence of cardiac risk factors. The electrocardiographic examinations were reviewed as well. The study cohort included 398 males (73%) and 142 females (27%), with a mean age of 36.2+/-4.3 years and a range of 12 to 40 years. Sixty-two patients (11.5%) had macroscopic fatty deposition of the RV myocardium.

CONCLUSIONS

Fatty replacement of the free wall of the RV is common, occurring in up to 11% of asymptomatic patients younger than 40 years of age undergoing cardiac screening examinations. No statistically significant association with cardiac risk factors or body mass index was found.

摘要

目的

右心室心肌纤维内可发现不同量的心肌内脂肪。我们旨在确定在接受冠状动脉疾病筛查的无症状、40 岁及以下患者的右心室(RV)内是否存在心肌内脂肪沉积。

材料和方法

回顾性分析了 540 例连续接受冠状动脉钙评分检查的 40 岁或以下的患者。

结果

由 2 名专门的心脏放射科医生对图像进行了回顾,并进行了以下具体观察:RV 内是否存在脂肪(按位置)、RV 大小是否正常或增大以及胸部其他部位是否存在脂肪沉积灶。从患者的病历中回顾了临床数据,并记录了以下信息:年龄、性别、体重指数和是否存在心脏危险因素。还回顾了心电图检查。研究队列包括 398 名男性(73%)和 142 名女性(27%),平均年龄为 36.2+/-4.3 岁,年龄范围为 12 岁至 40 岁。62 名患者(11.5%)的 RV 心肌有肉眼可见的脂肪沉积。

结论

RV 游离壁脂肪替代是常见的,在接受心脏筛查检查的无症状、40 岁以下患者中发生率高达 11%。未发现与心脏危险因素或体重指数有统计学显著相关性。

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