Department of Materials Science, University of Shiga Prefecture, Hassaka, Hikone 522-8533, Japan.
Biotechnol Lett. 2010 Sep;32(9):1299-303. doi: 10.1007/s10529-010-0294-9. Epub 2010 May 13.
Poly(epsilon-L-lysine) (epsilon-PL) is a naturally-occurring L-lysine homopolymer having antimicrobial activity. A newly-isolated strain of Streptomyces aureofaciens produced a short chain length epsilon-PL consisting of 5-20 residues at the highest production level of 4.5 g l(-1). This epsilon-PL had different spectra in terms of antimicrobial activity from the epsilon-PL that is now used as a food preservative. The high productivity was based on multiple metabolic pathways for L-lysine synthesis, and a great flux from L-lysine to epsilon-PL. The usefulness of this new epsilon-PL and its producing strain was discussed.
聚（ε-赖氨酸）（ε-PL）是一种天然存在的 L-赖氨酸均聚物，具有抗菌活性。一株新分离的金黄色链霉菌产生了一种短链长度的 ε-PL，其组成在最高生产水平为 4.5 g l(-1)时由 5-20 个残基组成。这种 ε-PL 在抗菌活性方面与现在用作食品防腐剂的 ε-PL 具有不同的谱。高生产力基于 L-赖氨酸合成的多种代谢途径，以及从 L-赖氨酸到 ε-PL 的巨大通量。讨论了这种新型 ε-PL 及其生产菌株的有用性。
