Beckmann H, Ossenkop C, Quellhorst E
J Dial. 1977;1(6):585-94. doi: 10.3109/08860227709037654.
The changes in the peripheral nerve function of three patients with chronic renal failure who were treated over a period of 1-1/2 to 2 years by hemofiltration have been analyzed in the form of a longitudinal study by quantitative measurements of vibratory perception threshold and nerve conduction velocity. Changes in vibratory perception threshold were measured in six patients both before and after treatment. Despite increased values of creatinine and BUN, an improvement in the peripheral nerve function of all patients undergoing hemofiltration could be observed, although vibratory perception and nerve conduction velocity did not return to normal. All of the vibratory perception threshold measurements made directly after hemofiltration showed an improved vibratory perception in comparison to the original values. A comparison of the measurement methods showed a good correlation and clearly indicated the advantage of vibratory perception threshold measurements as a means for the routine diagnosis of nephrogenic polyneuropathy.
通过对振动觉阈值和神经传导速度进行定量测量，以纵向研究的形式分析了3例慢性肾衰竭患者在1.5至2年期间接受血液滤过治疗时外周神经功能的变化。在6例患者治疗前后均测量了振动觉阈值。尽管肌酐和尿素氮值升高，但所有接受血液滤过治疗的患者外周神经功能均有改善，尽管振动觉和神经传导速度未恢复正常。与原始值相比，血液滤过治疗后直接进行的所有振动觉阈值测量均显示振动觉有所改善。测量方法的比较显示出良好的相关性，并清楚地表明了振动觉阈值测量作为肾源性多发性神经病常规诊断手段的优势。
