Veterinary Medical Diagnostic Laboratory, University of Missouri, 1600 East Rollins Street, Columbia, MO 65211, USA.
Vet Pathol. 2010 Sep;47(5):944-7. doi: 10.1177/0300985810369904. Epub 2010 May 13.
An 8-year-old castrated male mixed-breed dog had an ill-defined hemorrhagic and painful lesion in the base of the claw of the second digit of the right forelimb. Radiographically, the expansile and lytic lesion affected the distal phalanx. The digit was amputated and submitted for histologic examination. Histologically, the distal phalanx was largely replaced by a mass composed of variably sized cavernous vascular spaces lined by a single layer of flattened endothelial cells. A similar mass was in the subcutis adjacent to the distal phalanx. The benign vascular proliferation involving the medulla of bone and a second tissue type in this dog is consistent with skeletal-extraskeletal angiomatosis as described in humans. To the authors' knowledge, this is the first report of skeletal-extraskeletal angiomatosis in the veterinary literature.
一只 8 岁已去势的雄性混血杂种犬的右前肢第二指爪基部有一处界限不清的出血性和疼痛性病变。放射学检查显示，该扩张性和溶骨性病变累及远节指骨。对该指进行了截肢并送检组织学检查。组织学检查显示，远节指骨大部分被一个由大小不等的海绵状血管腔组成的肿块所取代，这些血管腔由单层扁平的内皮细胞排列而成。远节指骨附近的皮下组织中也有类似的肿块。涉及骨髓和另一种组织类型的良性血管增生与人类描述的骨外骨血管瘤一致。据作者所知，这是兽医文献中首例骨外骨血管瘤的报告。
