Can Fam Physician. 1971 Nov;17(11):45-7.
In new, previously untreated tuberculosis patients preference is given to treatment with major antituberculous drugs, namely Isoniazid, PAS and Streptomycin. The exchange of PAS with one of the recently introduced drugs (Rifampin, Ethambutol) should await the results of the therapeutic trials being conducted at various centers. In the meantime, these new drugs should be reserved for reactivation cases, for individuals hypersensitive to major antituberculous agents, or who are not responding satisfactorily to the routine therapy and for patients infected with organisms resistant to Isoniazid, PAS or Streptomycin.
在新的、未曾治疗过的肺结核患者中，优先选择使用主要抗结核药物进行治疗，即异烟肼、对氨基水杨酸钠和链霉素。将对氨基水杨酸钠替换为最近引入的一种药物（利福平、乙胺丁醇），应等待在各个中心进行的治疗试验结果。在此期间，这些新药应留作再激活病例、对主要抗结核药物过敏的个体、或对常规治疗反应不佳的个体，以及对异烟肼、对氨基水杨酸钠或链霉素耐药的感染患者使用。
