Emslie-Smith A M, Engel A G
Muscle Research Laboratory, Mayo Clinic, Rochester, MN 55905.
Neurology. 1991 Jun;41(6):936-9. doi: 10.1212/wnl.41.6.936.
Three adult patients, two with undifferentiated connective tissue disease and one with carcinoma, had a distinctive pathologic reaction pattern consisting of necrotizing myopathy, minimal cellular infiltration, and a microangiopathy with thick "pipestem" vessels and microvascular deposits of complement membrane attack complex. Quantitative analysis revealed focal capillary depletion. This pattern represents an immune-mediated microangiopathy and is distinct from that observed in other inflammatory myopathies.
三名成年患者，两名患有未分化结缔组织病，一名患有癌症，具有独特的病理反应模式，包括坏死性肌病、极少的细胞浸润，以及伴有粗大“烟斗柄样”血管和补体膜攻击复合物微血管沉积的微血管病。定量分析显示局灶性毛细血管减少。这种模式代表一种免疫介导的微血管病，与其他炎性肌病中观察到的模式不同。
