Moshkova A N, Erlykina E I, Khvatova E M
Biomed Khim. 2009 Nov-Dec;55(6):759-65.
The disturbances of blood circulation changes metabolism and energy reactions in the brain. The method of mathematical analysis is used for the study of the dependence between the activity mitochondrial creatine kinase (CK) and ATP level the brains of rats subjected to acute and chronic ischemia. A model describing this dependence under different conditions of the activity of organisms has been proposed. Thus it is possible to predict catalytic properties of CK based on ATP level.
血液循环紊乱会改变大脑中的新陈代谢和能量反应。采用数学分析方法来研究急性和慢性缺血大鼠大脑中线粒体肌酸激酶(CK)活性与ATP水平之间的依赖关系。已经提出了一个描述生物体在不同活动条件下这种依赖关系的模型。因此,基于ATP水平可以预测CK的催化特性。