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比较有和无磁共振兼容保温箱的新生儿 MRI 检查:在检查可行性和临床决策方面的优势。

Comparison of neonatal MRI examinations with and without an MR-compatible incubator: advantages in examination feasibility and clinical decision-making.

机构信息

Neonatal Intensive Care Unit, 1st Department of Obstetrics and Gynaecology, Semmelweis University, Budapest, Hungary.

出版信息

Eur J Paediatr Neurol. 2010 Sep;14(5):410-7. doi: 10.1016/j.ejpn.2010.03.005. Epub 2010 May 14.

Abstract

PURPOSE

To assess the utility of an MRI-compatible incubator (INC) by comparing.

METHODS

In a retrospective study, the clinical and radiological aspects of 129 neonatal MRI examinations during a 3 year period were analyzed. Routine protocols including fast spin-echo T2-weighted (w) sequences, axial T1w, Gradient-echo, diffusion sequences, and 3D T1 gradient-echo sequences were performed routinely, angiography and spectroscopy were added in some cases. Diffusion-tensor imaging was done in 50% of the babies examined in the INC and 26% without INC. Sequences, adapted from fetal MR-protocols were done in infants younger than 32 gestational weeks. Benefit from MR-information with respect to further management was evaluated.

RESULTS

The number of the examinations increased (30-99), while the mean age (43-38, 8 weeks of gestational age) and weight (3308-2766 g) decreased significantly with the use of the MR-compatible incubator. The mean imaging time (34, 43-30, 29 min) decreased, with a mean of one additionally performed sequence in the INC group. All infants received sedatives according to our anaesthetic protocol preceding imaging, but a repeated dose was never necessary (10% without INC) using the INC. Regarding all cases, MR-based changes in clinical management were initiated in 58%, while in 57% of cases the initial ultrasound diagnosis was changed or further specified.

CONCLUSIONS

The use of the INC enables the MR access of unstable infants with suspect CNS problems to the management, of whom is improved by MR information to significantly higher percentage, than without INC.

摘要

目的

通过比较来评估 MRI 兼容培养箱(INC)的实用性。

方法

在一项回顾性研究中,分析了三年内进行的 129 例新生儿 MRI 检查的临床和影像学方面。常规方案包括快速自旋回波 T2 加权(w)序列、轴位 T1w、梯度回波、扩散序列和 3D T1 梯度回波序列,在某些情况下还会进行血管造影和光谱分析。在使用 INC 的婴儿中,50%接受了扩散张量成像检查,而在未使用 INC 的婴儿中,这一比例为 26%。在小于 32 孕周的婴儿中,采用了来自胎儿 MR 方案的序列。评估了从 MR 信息中获得的对进一步治疗的益处。

结果

检查数量增加(30-99),而使用 MRI 兼容培养箱后,平均年龄(43-38,8 周胎龄)和体重(3308-2766 克)显著降低。成像时间(34,43-30,29 分钟)缩短,INC 组平均多进行了一个序列。所有婴儿在成像前根据我们的麻醉方案接受镇静剂,但在使用 INC 时,从未需要重复剂量(无 INC 组为 10%)。所有病例中,58%的病例基于 MR 改变了临床管理,57%的病例改变或进一步明确了初始超声诊断。

结论

使用 INC 可使怀疑有中枢神经系统问题的不稳定婴儿能够进行 MRI 检查,并通过 MRI 信息显著提高了其管理的比例。

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