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基于人群的研究中足部骨关节炎的放射学定义的系统评价。

A systematic review of radiographic definitions of foot osteoarthritis in population-based studies.

机构信息

Arthritis Research Campaign National Primary Care Centre, Primary Care Sciences, Keele University, Keele, Staffordshire ST5 5BG, United Kingdom.

出版信息

Osteoarthritis Cartilage. 2010 Aug;18(8):1027-35. doi: 10.1016/j.joca.2010.05.005. Epub 2010 May 28.

Abstract

OBJECTIVE

To identify the methods used in population-based epidemiological studies to diagnose radiographic foot osteoarthritis (OA) and to estimate the population prevalence of radiographic foot OA.

METHOD

Electronic databases searched included Medline, Embase, CINAHL and Ageline (inception to May 2009). The search strategy combined search terms for radiography, OA, foot, and specific foot joints. Predetermined selection criteria were applied. Data extracted from each paper included: sample population, radiographic views taken, foot joints examined, scoring system used, definition of OA applied, reliability of radiographic scoring and prevalence of radiographic OA in the foot.

RESULTS

Titles and abstracts of 1035 papers were reviewed and full-texts of 21 papers were obtained. Fifteen papers met inclusion criteria and a further 12 papers were included after screening references. Radiographic views were frequently not specified (NS) but a combination of antero-posterior (AP) and lateral (Lat) views was most commonly reported. The first metatarsophalangeal (MTP) joint was the most commonly examined joint (n=20, 74%). Nineteen studies (70%) used the Kellgren and Lawrence (K&L) grading system, 95% of which defined OA as K&L grade> or =2. Estimates of the prevalence of radiographic first MTP joint OA (defined as K&L> or =2) in middle-aged to older adults ranged from 6.3 to 39%. Significant statistical heterogeneity prevented pooling of prevalence estimates.

CONCLUSION

There are comparatively few studies examining radiographic foot OA. Existing studies mainly focus on the first MTP joint and use the K&L grading system. Future studies are needed to quantify the prevalence of radiographic OA at the different joint complexes within the foot.

摘要

目的

确定在基于人群的流行病学研究中用于诊断放射影像学足部骨关节炎(OA)的方法,并估计放射影像学足部 OA 的人群患病率。

方法

检索的电子数据库包括 Medline、Embase、CINAHL 和 Ageline(从创建至 2009 年 5 月)。该检索策略将放射学、OA、足部和特定足部关节的检索词结合起来。应用了预定的选择标准。从每篇论文中提取的数据包括:样本人群、拍摄的放射学影像、检查的足部关节、使用的评分系统、应用的 OA 定义、放射学评分的可靠性以及足部放射影像学 OA 的患病率。

结果

共查阅了 1035 篇论文的标题和摘要,并获得了 21 篇论文的全文。15 篇论文符合纳入标准,在筛选参考文献后又纳入了 12 篇论文。放射学影像经常未明确规定(NS),但最常报告的是前后位(AP)和侧位(Lat)影像的组合。第一跖趾关节(MTP)是最常检查的关节(n=20,74%)。19 项研究(70%)使用了 Kellgren 和 Lawrence(K&L)分级系统,其中 95%将 OA 定义为 K&L 分级>或=2。中老年人放射影像学第一 MTP 关节 OA(定义为 K&L>或=2)的患病率估计值范围为 6.3%至 39%。由于存在显著的统计学异质性,无法对患病率估计值进行汇总。

结论

研究放射影像学足部 OA 的研究相对较少。现有研究主要集中在第一 MTP 关节,并使用 K&L 分级系统。需要进一步研究来量化足部不同关节复合体的放射影像学 OA 患病率。

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