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三光子能量吸收法测量骨矿物质的理论与实验限度

Theoretical and experimental limits of triple photon energy absorptiometry in the measurement of bone mineral.

作者信息

Kotzki P O, Mariano-Goulart D, Rossi M

机构信息

Department of Nuclear Medicine, Lapeyronie Hospital, Montpellier, France.

出版信息

Phys Med Biol. 1991 Apr;36(4):429-37. doi: 10.1088/0031-9155/36/4/002.

DOI:10.1088/0031-9155/36/4/002
PMID:2047394
Abstract

Theoretical and experimental studies have been conducted to explore the possibilities of triple photon energy absorptiometry in the measurement of bone mineral content. The purpose of this technique is to correct the measured bone mineral density for fat and soft tissues. However, theoretical considerations lead us to doubt the precision and accuracy of such measurements. In a first approximation the absorption coefficient can be split into Compton and photoelectric energy-independent factors. A consequence of such a model is the impossibility of finding more than two independent mass attenuation coefficients for different energies. The existence of an energy-dependent third factor may justify the use of triple photon energy absorptiometry but experimental tests and numerical simulations have shown that its value is too low for triple photon energy absorptiometry to be considered as an adequate method for the measurement of bone mineral content.

摘要

已开展理论和实验研究,以探索三光子能量吸收测定法在测量骨矿物质含量方面的可能性。该技术的目的是校正脂肪和软组织对测得的骨矿物质密度的影响。然而,理论思考使我们怀疑此类测量的精度和准确性。在一阶近似中,吸收系数可分为康普顿和光电能量无关因子。这种模型的一个结果是,对于不同能量,不可能找到超过两个独立的质量衰减系数。能量相关的第三个因子的存在可能证明三光子能量吸收测定法的使用是合理的,但实验测试和数值模拟表明,其值过低,以至于三光子能量吸收测定法不能被视为测量骨矿物质含量的适当方法。

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