Protective effects of gamma-hydroxybutyrate on alloxan induced diabetes in mice.
作者信息
Pierrefiche G, Topall G, Henriet I, Laborit H
机构信息
Laboratoire d'Eutonologie, Hopital Boucicaut, Paris, France.
出版信息
Res Commun Chem Pathol Pharmacol. 1991 Mar;71(3):309-19.
PMID:2047574
Abstract
Gamma-hydroxybutyrate (GHB) administered to mice prior to alloxan antagonizes its diabetogenic action in a dose dependent fashion and up to 96 hours after injection. Results are discussed on the basis of free radical formation by alloxan and of the metabolic property of GHB which is known to increase the rate of operation of the pentose phosphate pathway.
摘要
Zotero 插件