Hsu Vasha, Grant David C, Dubey J P, Zajac Anne M, Lindsay David S
Department of Biomedical Sciences and Pathobiology, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, VA 24061-0342, USA.
J Parasitol. 2010 Aug;96(4):800-1. doi: 10.1645/GE-2449.1.
Sarcocystis neurona is best known as the causative agent of equine protozoal myeloencephalitis of horses in the Americas. Domestic cats ( Felis domesticus ) were the first animals described as an intermediate host for S. neurona . However, S. neurona -associated encephalitis has also been reported in naturally infected cats in the United States. Thus, cats can be implicated in the life cycle of S. neurona as natural intermediate hosts. The present study examined the seroprevalence of IgG antibodies to merozoites of S. neurona in populations of domestic cats from Virginia and Pennsylvania. Overall, sera or plasma from 441 cats (Virginia = 232, Pennsylvania = 209) were tested by an indirect immunofluorescent assay at a 1ratio50 dilution. Antibodies to S. neurona were found in 32 (7%) of 441 cats. Of these, 22 (9%) of the 232 cats from Virginia and 10 (5%) of the 209 cats from Pennsylvania were seropositive for S. neurona .
肉孢子虫是美洲马属动物原生动物脑脊髓炎的病原体。家猫(Felis domesticus)是最早被描述为肉孢子虫中间宿主的动物。然而,在美国自然感染的猫中也报告了与肉孢子虫相关的脑炎。因此,猫可作为自然中间宿主参与肉孢子虫的生命周期。本研究检测了弗吉尼亚州和宾夕法尼亚州家猫群体中针对肉孢子虫裂殖子的IgG抗体血清阳性率。总体而言,对来自441只猫(弗吉尼亚州 = 232只,宾夕法尼亚州 = 209只)的血清或血浆进行了间接免疫荧光检测,稀释比例为1:50。在441只猫中有32只(7%)检测到针对肉孢子虫的抗体。其中,来自弗吉尼亚州的232只猫中有22只(9%)、来自宾夕法尼亚州的209只猫中有10只(5%)对肉孢子虫血清呈阳性。