Dubey J P, Howe D K, Furr M, Saville W J, Marsh A E, Reed S M, Grigg M E
United States Department of Agriculture, Agricultural Research Service, Animal Parasitic Diseases Laboratory, Beltsville Agricultural Research Center, Building 1001, Beltsville, MD 20705-2350, USA.
M.H. Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, KY 40546-0099, USA.
Vet Parasitol. 2015 Apr 15;209(1-2):1-42. doi: 10.1016/j.vetpar.2015.01.026. Epub 2015 Feb 7.
Equine protozoal myeloencephalitis (EPM) is a serious disease of horses, and its management continues to be a challenge for veterinarians. The protozoan Sarcocystis neurona is most commonly associated with EPM. S. neurona has emerged as a common cause of mortality in marine mammals, especially sea otters (Enhydra lutris). EPM-like illness has also been recorded in several other mammals, including domestic dogs and cats. This paper updates S. neurona and EPM information from the last 15 years on the advances regarding life cycle, molecular biology, epidemiology, clinical signs, diagnosis, treatment and control.
马属动物原虫性脑脊髓炎（EPM）是马的一种严重疾病，对兽医来说，其治疗仍是一项挑战。原生动物神经肉孢子虫最常与EPM相关。神经肉孢子虫已成为海洋哺乳动物，尤其是海獭（Enhydra lutris）死亡的常见原因。在包括家犬和家猫在内的其他几种哺乳动物中也记录到了类似EPM的疾病。本文更新了过去15年中关于神经肉孢子虫和EPM在生命周期、分子生物学、流行病学、临床症状、诊断、治疗和控制方面进展的信息。
