Aynaoğlu Gülşah, Durdağ Gülşen Doğan, Ozmen Batuhan, Söylemez Feride
Ankara University School of Medicine, Department of Obstetrics and Gynecology, Ankara, Turkey.
J Matern Fetal Neonatal Med. 2010 Sep;23(9):1053-5. doi: 10.3109/14767050903440463.
To present a rare case with factor VII deficiency (FVIID) that first diagnosed during pregnancy, and to disccuss the ante-, peri- and postpartum management.
A case report and review of the literature.
FVIID was diagnosed for the first time in a 23-year-old pregnant woman at the 24th week of gestation due to complaint of intermittent epistaxis. She was successfully treated by ante-, peripartum and postpartum replacement of recombinant FVII (rFVII). She was uneventfully discharged on the 3rd postoperative day and referred to hematology department for further follow-up.
FVIID, a rare cause of ante- and postpartum hemorrhages that may differently present by other hemorrhages (i.e.: epistaxis), can be optimally managed with replacement of rFVII.
报告1例孕期首次诊断为Ⅶ因子缺乏症（FVIID）的罕见病例，并探讨产前、产时及产后的管理。
病例报告及文献复习。
一名23岁孕妇在妊娠24周时因间歇性鼻出血首次诊断为FVIID。通过产前、围产期和产后重组Ⅶ因子（rFVII）替代治疗，她获得成功治疗。术后第3天顺利出院，并转诊至血液科进行进一步随访。
FVIID是产前和产后出血的罕见原因，可能与其他出血（如鼻出血）表现不同，通过rFVII替代治疗可得到最佳管理。
