Dahllöf G, Forsberg C M, Näsman M, Mattsson T, Modéer T, Borgström B, Bolme P, Ringdén O
Department of Pedodontics, School of Dentistry, Karolinska Institutet, Stockholm, Sweden.
Scand J Dent Res. 1991 Feb;99(1):44-7. doi: 10.1111/j.1600-0722.1991.tb01021.x.
The effect of growth hormone (GH) treatment on craniofacial development was studied in five children exhibiting growth retardation following bone marrow transplantation. Linear and angular measurements were made on lateral radiographic cephalograms taken prior to the start of GH treatment and after an average treatment time of 1.2 yr. The results showed that the mean growth increments of mandibular length in the GH treated children, exceeded the corresponding values of the control group by 150% during the period of investigation. It is suggested that this dimensional increase in the patients was due to GH stimulation on the chondral growth process in the mandibular condyles.
研究了生长激素（GH）治疗对五名骨髓移植后生长发育迟缓儿童颅面发育的影响。在开始GH治疗前及平均治疗1.2年后，对患者进行头颅侧位X线片拍摄，并进行线性和角度测量。结果显示，在研究期间，接受GH治疗的儿童下颌长度的平均生长增量比对照组相应值高出150%。提示患者下颌骨尺寸增加是由于GH刺激下颌髁突软骨生长过程所致。
