Hansen E S
Institute of Community Health, University of Odense, Denmark.
Scand J Work Environ Health. 1991 Feb;17(1):20-4. doi: 10.5271/sjweh.1739.
This study was conducted to investigate the adverse health effects of exposure to bitumen fumes. A cohort of 679 mastic asphalt workers was followed from 1959 to 10 June 1986, during this period 169 deaths occurred. The overall standardized mortality ratio (SMR) was 163 (95% confidence interval (95% CI) 141-190), the SMR was 225 (95% CI 172-288) for cancer and 223 (95% CI 130-358) for external causes. Among persons aged 40 to 89 years, significant increases were seen for lung cancer (SMR 290, 95% CI 188-429), nonpulmonary cancer (SMR 200, 95% CI 141-276), and liver cirrhosis (SMR 467, 95% CI 188-962). Bronchitis, emphysema, and asthma also occurred in excess (SMR 207, 95% CI 95-393). In conclusion, the inhalation of bitumen fumes may have contributed to the elevated mortality from cancer and respiratory diseases among mastic asphalt workers.
本研究旨在调查接触沥青烟对健康的不良影响。对一组679名玛蹄脂沥青工人进行了从1959年至1986年6月10日的随访，在此期间有169人死亡。总体标准化死亡比（SMR）为163（95%置信区间（95%CI）141 - 190），癌症的SMR为225（95%CI 172 - 288），外部原因的SMR为223（95%CI 130 - 358）。在40至89岁的人群中，肺癌（SMR 290，95%CI 188 - 429）、非肺癌（SMR 200，95%CI 141 - 276）和肝硬化（SMR 467，95%CI 188 - 962）的发病率显著增加。支气管炎、肺气肿和哮喘的发病率也过高（SMR 207，95%CI 95 - 393）。总之，吸入沥青烟可能导致了玛蹄脂沥青工人癌症和呼吸系统疾病死亡率的升高。
