Ballonzoli Laurent, Bourcier Tristan
Service d'Opthalmologie, Nouvel Hôpital Civil, Strasbourg, France.
Therapie. 2010 Mar-Apr;65(2):115-20. doi: 10.2515/therapie/2010002. Epub 2010 May 19.
The increasing use of immunosuppressive (IS) drugs in transplants or in systemic diseases, implies a long period of treatment and to be aware of possible side effects. These drugs can be used alone or in combination with steroids. This review deals with the issue of ocular side effects of the most used IS drugs, including steroids. Data were collected from Medline using Pubmed software. We first describe specific complication of each drug and then conclude on major common toxicity represented by opportunistic infections and induced cancers.
免疫抑制（IS）药物在移植或全身性疾病中的使用日益增加，这意味着需要长期治疗，并要注意可能出现的副作用。这些药物可以单独使用，也可以与类固醇联合使用。本综述探讨了最常用的免疫抑制药物（包括类固醇）的眼部副作用问题。数据通过PubMed软件从Medline收集。我们首先描述每种药物的特定并发症，然后总结以机会性感染和诱发癌症为代表的主要常见毒性。
