Carnahan M C, Goldstein D A
Eye Institute, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Curr Opin Ophthalmol. 2000 Dec;11(6):478-83. doi: 10.1097/00055735-200012000-00016.
Topical ophthalmic, oral, and intravenous corticosteroids have long been associated with ocular side effects. Recent data suggest that inhaled corticosteroids are also associated with the development of cataract and increased intraocular pressure. Thus far, nasally administered steroids have not been associated with the same effects. Local injection of steroids, even at sites far from the eye, have been associated with the development of cataract, glaucoma, and even retinal and choroidal emboli. Any physician prescribing corticosteroids should be aware of these potential ocular side effects and should advise patients accordingly.
局部眼用、口服和静脉注射皮质类固醇长期以来一直与眼部副作用相关。最近的数据表明,吸入性皮质类固醇也与白内障的发生和眼压升高有关。到目前为止,经鼻给药的类固醇尚未发现有同样的影响。即使在远离眼睛的部位局部注射类固醇,也与白内障、青光眼甚至视网膜和脉络膜栓塞的发生有关。任何开具皮质类固醇处方的医生都应了解这些潜在的眼部副作用,并应相应地告知患者。