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百草枯中毒:诊断极具挑战性。

Paraquat ingestion: a challenging diagnosis.

机构信息

Department of Pediatrics, Duke University Medical Center, DUMC Box 3046, Durham, NC 27710, USA.

出版信息

Pediatrics. 2010 Jun;125(6):e1505-9. doi: 10.1542/peds.2009-2601. Epub 2010 May 17.

Abstract

Paraquat is an herbicide that is highly toxic to humans. Pediatric ingestion has become uncommon in the United States because of preventative efforts. We report here an unintentional, fatal paraquat ingestion by an 8-year-old child. Storage in an inappropriate container, confusion between herbicide trade names, nonspecific symptoms, and a delay in follow-up produced challenges in the diagnosis. In the absence of a clear history of ingestion, paraquat poisoning should be suspected in children who develop skin and mucous membrane burns, gastrointestinal symptoms, acute kidney injury, and respiratory failure.

摘要

百草枯是一种对人类毒性极高的除草剂。由于预防措施,在美国,儿科患者摄入百草枯的情况已不常见。我们在此报告一例 8 岁儿童意外摄入百草枯导致的致命病例。百草枯被存放在不合适的容器中,除草剂商品名混淆,症状不具特异性,以及随访延迟,这些都给诊断带来了挑战。在没有明确摄入史的情况下,如果儿童出现皮肤和黏膜灼伤、胃肠道症状、急性肾损伤和呼吸衰竭,应怀疑百草枯中毒。

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