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慢性脊髓病中反复发作的大块肺栓塞:病例报告。

Recurrent, massive pulmonary embolism in chronic myelopathy: a case report.

机构信息

Research Service, VA Boston Healthcare System, and Harvard Medical School, Boston, MA, USA.

出版信息

Spinal Cord. 2011 Feb;49(2):318-20. doi: 10.1038/sc.2010.54. Epub 2010 May 18.

Abstract

STUDY DESIGN

Case report.

OBJECTIVES

The aim of this report was to describe an example of pulmonary embolism (PE), recently suggested to be highly prevalent in persons with chronic spinal cord lesions.

SETTING

Veterans Affairs Hospital, Boston, MA, USA.

METHODS

Chart review.

RESULTS

A 60-year-old man with paraplegia, T10 motor complete, underwent laminectomy for correction of an arteriovenous malformation. After 41 days, he sustained a massive PE-suggested by right bundle branch block (RBBB) on an electrocardiogram (ECG) and diagnosed by perfusion lung scanning. He was treated with anticoagulants, the lung scan and RBBB resolving within 1 month of initiating treatment. After 5 years, he developed vertebral osteomyelitis at L5-S1 and was treated with antibiotics and bed rest. After 7 days, he was mobilized to a wheelchair, and during a transfer back to bed, he developed anxiety, dyspnea, fluctuating consciousness, low blood pressure and RBBB, absent by ECG 4 days earlier. He expired 20 min after onset of symptoms. The autopsy revealed a fresh thromboembolus occluding both main stem branches of the pulmonary artery.

CONCLUSION

Massive PE after surgery in a patient with chronic paraplegia recurred 5 years later in association with severe infection and mobilization after bed rest, which resulted in death.

摘要

研究设计

病例报告。

目的

本报告旨在描述一例近期被认为在慢性脊髓损伤患者中普遍存在的肺栓塞(PE)。

地点

美国马萨诸塞州波士顿退伍军人事务医院。

方法

病历回顾。

结果

一名 60 岁男子,截瘫,T10 运动完全丧失,因动静脉畸形行椎板切除术。41 天后,他出现了右束支传导阻滞(RBBB)的心电图(ECG),提示发生了大面积的 PE,并通过肺灌注扫描进行了诊断。他接受了抗凝治疗,肺部扫描和 RBBB 在开始治疗后 1 个月内得到解决。5 年后,他在 L5-S1 发生了脊椎骨髓炎,接受了抗生素和卧床休息治疗。7 天后,他被转移到轮椅上,在转移回床上的过程中,他出现了焦虑、呼吸困难、意识波动、低血压和 RBBB,而在 4 天前的心电图上并没有 RBBB。他在症状出现后 20 分钟死亡。尸检显示新鲜血栓栓塞了肺动脉的两支主干。

结论

慢性截瘫患者手术后发生的大面积 PE,5 年后因严重感染和卧床休息后的活动而再次发生,导致患者死亡。

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