Arch Gynecol Obstet. 2011 Jan;283(1):135-7. doi: 10.1007/s00404-010-1507-0. Epub 2010 May 18.
Reports have indicated that maternal administration of ritodrine increased the ventricular rate and thus ameliorated signs of heart failure in a fetus with complete atrioventricular block (CAVB). A fetus from a mother without the anti-SS-A/SS-B antibody had CAVB, with atrial rate 148-154 bpm and ventricular rate 53-57 bpm. After maternal administration of ritodrine, the ventricular rate increased to 60-65 bpm, and then sinus rhythm resumed. Ritodrine may not only increase the ventricular rate but also induce sinus rhythm in a fetus with CAVB.
有报道称,利托君的母体给药增加了心室率,从而改善了完全性房室传导阻滞(CAVB)胎儿的心力衰竭迹象。一位没有抗 SS-A/SS-B 抗体的母亲的胎儿患有 CAVB,心房率为 148-154 bpm,心室率为 53-57 bpm。利托君母体给药后,心室率增加至 60-65 bpm,随后窦性节律恢复。利托君不仅可以增加心室率,还可以诱导 CAVB 胎儿的窦性节律。