MRC Unit on Anxiety and Stress Disorders, Stellenbosch University, Cape Town, South Africa.
Psychol Health Med. 2010 May;15(3):278-87. doi: 10.1080/13548501003615258.
Maternal postpartum depression poses significant risks for mother-child interaction and long-term infant outcomes. Human immunodeficiency virus (HIV) status has also been implicated in the development of postpartum depression, but the association between maternal depression and infant social behavior in the context of HIV infection has not been fully investigated. First, we examined the relationship between maternal postpartum depression and infant social withdrawal at 10-12 months of age in HIV-infected mothers and infants. Second, we ascertained whether infant social withdrawal could be significantly predicted by maternal postpartum depression. The sample consisted of 83 HIV-infected mother-infant dyads. Mothers were assessed for postpartum depression with the Edinburgh Postnatal Depression Scale (EPDS), and infant social withdrawal behavior was rated using the Modified Alarm Distress Baby Scale (m-ADBB). 42.2% of the mothers scored above the cut-off point for depression on the EPDS, and a third of infants (31%) were socially withdrawn. Notably, maternal depression did not predict infant social withdrawal as measured by the m-ADBB. Infant social withdrawal was also not significantly associated with failure to thrive or gender. These preliminary findings need further investigation with respect to the impact on long-term neurodevelopmental and behavioral outcomes.
产妇产后抑郁症对母婴互动和婴儿长期结局存在重大风险。人类免疫缺陷病毒（HIV）感染也与产后抑郁症的发生有关，但在 HIV 感染背景下，产妇抑郁与婴儿社会行为之间的关系尚未得到充分研究。首先，我们研究了 HIV 感染产妇和婴儿中产妇产后抑郁症与婴儿 10-12 月龄社会退缩之间的关系。其次，我们确定了婴儿社会退缩是否可以被产妇产后抑郁症显著预测。该样本包括 83 对 HIV 感染母婴对。使用爱丁堡产后抑郁量表（EPDS）评估母亲的产后抑郁症，使用改良警报苦恼婴儿量表（m-ADBB）评估婴儿的社会退缩行为。EPDS 上有 42.2%的母亲得分高于抑郁的临界值，三分之一的婴儿（31%）有社会退缩。值得注意的是，m-ADBB 测量的产妇抑郁并未预测婴儿的社会退缩。婴儿社会退缩也与生长发育不良或性别无关。这些初步发现需要进一步研究，以了解其对长期神经发育和行为结果的影响。
