Grabner A, Fischer A
I. Medizinischen Tierklinik, Ludwig-Maximilians-Universität München.
Tierarztl Prax. 1991 Feb;19(1):68-73.
In a retrospective study of 38 horses with Borna encephalitis which were clinically and histopathologically examined in the "I. Medizinische Tierklinik" in Munich between 1977 and 1990, the epidemiology, the clinical symptomatic and the diagnostic procedures available are presented. Indirect immunofluorescence showed antibodies in the serum of 12 out of 29 cases (41%) and in the cerebrospinal fluid (CSF) of 17 out of 28 cases (61%). The evaluation of 23 cases in which indirect immunofluorescence of serum and CSF, and also the post mortem virological and histopathological examination of the brain were performed, showed that a diagnosis was made in 61% of the cases before death. In 39% the diagnosis of Borna disease could only be reached post mortem.
在一项对1977年至1990年间于慕尼黑“第一兽医临床医院”接受临床和组织病理学检查的38匹患有博尔纳脑炎马匹的回顾性研究中,介绍了其流行病学、临床症状及可用的诊断方法。间接免疫荧光显示,29例中有12例(41%)血清中有抗体,28例中有17例(61%)脑脊液(CSF)中有抗体。对23例进行了血清和脑脊液间接免疫荧光检查以及死后脑部病毒学和组织病理学检查的病例评估显示,61%的病例在死亡前做出了诊断。39%的病例只能在死后做出博尔纳病的诊断。