Suppr超能文献

经皮胆红素检测——比较BiliChek®和JM 103®在某地区产后病房的准确性

Transcutaneous bilirubin--comparing the accuracy of BiliChek® and JM 103® in a regional postnatal unit.

作者信息

Qualter Yvonne M, Allen Nicholas M, Corcoran John D, O'Donovan Donough J

机构信息

Department of Midwifery, Galway University Hospital, Newcastle Road, Galway, Ireland.

出版信息

J Matern Fetal Neonatal Med. 2011 Feb;24(2):267-70. doi: 10.3109/14767058.2010.484471. Epub 2010 May 19.

Abstract

OBJECTIVE

Transcutaneous bilirubin (TcB) has the potential to reduce serum bilirubin sampling. During a recent survey on the use of TcB in postnatal units in the Republic of Ireland, we identified that only 58% of the 19 units were using TcB and that only two devices were in use, the BiliChek® and JM 103®. We aimed to evaluate and compare these two devices in a regional postnatal unit.

METHODS

To evaluate and compare the accuracy of the BiliChek® and JM 103®, we studied simultaneous TcB and total serum bilirubin (TSB) measurements from a population of jaundiced term and near term infants. We evaluated each device with regard to correlation with TSB and potential to safely reduce serum bilirubin testing.

RESULTS

Both TcB devices strongly correlated with TSB (r = 0.88 for BiliChek® and r = 0.70 for JM 103®. The BiliChek® and JM 103® were accurate up to cut-off values of 200 μmol/L and 180 μmol/L, respectively. Using Bhutani's nomogram, 100% sensitivity was achieved using the 75th percentile for BiliChek® and the 40th percentile for JM 103®.

CONCLUSION

Both TcB devices correlated closely with moderately increased TSB levels and are suitable screening tools to identify jaundiced infants that require a serum bilirubin, with upper limit cut-off values. Both devices reduced the need for TSB levels. We found the BiliChek® slightly more accurate than the JM 103® for our study population. TcB however, is not in widespread use.

摘要

目的

经皮胆红素(TcB)检测有减少血清胆红素采样的潜力。在近期一项关于爱尔兰共和国产后病房使用TcB的调查中,我们发现19个病房中只有58%在使用TcB,且仅使用了两种设备,即BiliChek®和JM 103®。我们旨在对一个地区性产后病房中的这两种设备进行评估和比较。

方法

为评估和比较BiliChek®和JM 103®的准确性,我们对一组足月和近足月黄疸婴儿同时进行了TcB和总血清胆红素(TSB)测量。我们评估了每种设备与TSB的相关性以及安全减少血清胆红素检测的潜力。

结果

两种TcB设备与TSB均高度相关(BiliChek®的r = 0.88,JM 103®的r = 0.70)。BiliChek®和JM 103®分别在截断值200 μmol/L和180 μmol/L时准确。使用布塔尼列线图,BiliChek®采用第75百分位数、JM 103®采用第40百分位数时灵敏度达到100%。

结论

两种TcB设备与中度升高的TSB水平密切相关,是识别需要进行血清胆红素检测的黄疸婴儿的合适筛查工具,有上限截断值。两种设备都减少了对TSB检测的需求。对于我们的研究人群,我们发现BiliChek®比JM 103®稍准确。然而,TcB并未得到广泛应用。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验