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强迫症患者的家庭适应:与症状维度、临床和家庭特征的关系。

Family accommodation in obsessive-compulsive disorder: Relation to symptom dimensions, clinical and family characteristics.

机构信息

Mood and Anxiety Disorders Unit, Department of Neurosciences, University of Turin, Italy.

出版信息

Psychiatry Res. 2010 Sep 30;179(2):204-11. doi: 10.1016/j.psychres.2009.06.008. Epub 2010 May 18.

Abstract

Family accommodation is the term used to indicate the process whereby family members of patients with obsessive-compulsive disorder (OCD) assist or participate in the patients' rituals. Family accommodation is a relatively under-researched phenomenon in OCD but an important one because it may be predictive of poor treatment outcome. This study systematically examined several socio-demographic and clinical variables that are associated with family accommodation in a well-characterized sample of adult patients and their healthy family members. Experienced clinicians administered the Family Accommodation Scale (FAS) to 141 psychopathology-free family members cohabiting with 97 patients with OCD. The items of the FAS were first subjected to principal component analysis (PCA) and the resulting domains of family accommodation (Participation, Modification, and Distress and Consequences) introduced as dependent variables in a series of multiple regression models assessing the relationship between family accommodation domains and a wide range of clinical variables, including Axis I and II psychopathology and symptom dimensions derived from the Yale-Brown Obsessive-Compulsive Scale (YBOCS) Symptom Checklist. The results showed that family accommodation was common, with the provision of reassurance, participation in rituals and assisting the patient in avoidance being the most frequent practices (occurring on a daily basis in 47%, 35%, and 43% of family members, respectively). The PCA of the YBOCS Symptom Checklist yielded four symptom dimensions, which were identical to those previously identified in the international literature. Multiple linear regression analyses showed that a higher score on the contamination/washing symptom dimension and a positive family history for an anxiety disorder other than OCD (referring to a family member other than the participant in this study) predicted greater scores on several domains of family accommodation. Our study confirms that family accommodation is frequent and distressing in psychopathology-free family members cohabiting with adult OCD patients. Family accommodation is particularly frequent and distressing when the patient has prominent contamination/washing symptoms and/or when another family member has a history of an anxiety disorder. Such families may be more likely to benefit from family-based interventions but this remains to be tested in controlled trials.

摘要

家庭顺应是指患者强迫症(OCD)的家庭成员协助或参与患者仪式的过程。家庭顺应在 OCD 中是一个相对研究不足但很重要的现象,因为它可能预示着治疗效果不佳。本研究系统地检查了几个与 OCD 患者及其健康家庭成员的特征样本中的家庭顺应相关的社会人口统计学和临床变量。经验丰富的临床医生使用家庭顺应量表(FAS)对 141 名无精神病理学的家庭同住者进行了评估,这些同住者与 97 名 OCD 患者一起居住。FAS 的项目首先进行主成分分析(PCA),并将家庭顺应的各个领域(参与、修改、痛苦和后果)作为因变量引入一系列多元回归模型中,以评估家庭顺应领域与广泛的临床变量之间的关系,包括轴 I 和 II 精神病理学和从耶鲁-布朗强迫症量表(YBOCS)症状检查表中得出的症状维度。结果表明,家庭顺应很常见,提供安慰、参与仪式和帮助患者避免是最常见的做法(分别有 47%、35%和 43%的家庭成员每天都这样做)。YBOCS 症状检查表的 PCA 得出了四个症状维度,与国际文献中先前确定的维度相同。多元线性回归分析表明,污染/洗涤症状维度的得分较高,以及 OCD 以外的焦虑障碍的阳性家族史(指除了参与本研究的家庭成员以外的家庭成员),预测了家庭顺应的几个领域的得分更高。我们的研究证实,在与 OCD 成年患者同住的无精神病理学的家庭成员中,家庭顺应是常见的,而且令人痛苦。当患者有明显的污染/洗涤症状和/或当另一个家庭成员有焦虑障碍病史时,家庭顺应更为常见和痛苦。这些家庭可能更受益于基于家庭的干预措施,但这仍有待对照试验的检验。

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