Fratiglioni L, Inzitari D, Arfaioli C, Nencini P, Ginanneschi A, Pracucci G, Zuppiroli A, Italiani G, Amaducci L
Department of Neurological & Psychiatric Sciences, University of Florence, Italy.
Acta Neurol Scand. 1991 Apr;83(4):214-20. doi: 10.1111/j.1600-0404.1991.tb04685.x.
A case-control study was based on "unselected" transient ischemic attacks (TIAs) in a middle-aged Italian population. The identified cases included 52 prevalent and 25 incident TIAs. There was an incidence rate ratio (female/male) of 1.8 for definite cases. Comparison with the whole population for medical history of hypertension, diabetes and heart attack showed age/sex-adjusted odds ratios of 4.3, 2.1, 7.9 for incident cases. The results were similar when a more detailed investigation of risk factors was performed with all the cases and a random sample of the controls. Moreover, female sex had an odds ratio for incident cases of 3.3 (95% confidence interval 1.0-11.3) after adjustment for age and presence of all the main risk factors. The presence of at least one cardiopathy showed an odds ratio of 8.3 for incident cases (95% confidence interval 2.4-28.4).
一项病例对照研究基于意大利中年人群中“未经过筛选”的短暂性脑缺血发作（TIA）。所确定的病例包括52例现患TIA和25例新发TIA。确诊病例的发病率比（女性/男性）为1.8。将新发病例的高血压、糖尿病和心脏病病史与整个人口进行比较，年龄/性别调整后的优势比分别为4.3、2.1、7.9。当对所有病例和对照组的随机样本进行更详细的危险因素调查时，结果相似。此外，在对年龄和所有主要危险因素进行调整后，女性新发病例的优势比为3.3（95%置信区间1.0 - 11.3）。至少存在一种心脏病时，新发病例的优势比为8.3（95%置信区间2.4 - 28.4）。
