Institute of Public Health-Health Economics, University of Southern Denmark, Odense C, Denmark.
Eur J Public Health. 2011 Jun;21(3):323-8. doi: 10.1093/eurpub/ckq063. Epub 2010 May 19.
Little is known about characteristics of patients receiving allergen-specific immunotherapy. Identifying obstacles to appropriate treatment according to guidelines may facilitate the development of strategies aiming at improved treatment of patients with allergic respiratory diseases. The objective of this study was to investigate differences in disease severity, demographic and socioeconomic status between allergic rhinitis patients receiving allergen-specific immunotherapy and allergic rhinitis patients not receiving allergen-specific immunotherapy.
A total of 366 patients were studied of whom 210 were going to receive subcutaneously administrated immunotherapy (SIT) against grass pollen and/or house dust mite allergy. The severity of rhino-conjunctivitis (hay fever) and/or asthma was classified according to international guidelines. The questionnaires included an EQ-5D visual analogue scale instrument and some socio-economic questions.
Severity of disease, young age, high level of education as well as greater perceived impairment of health-related quality of life due to allergic symptoms were significantly associated with use of SIT. Somewhat unexpectedly, household income was not associated with use of SIT.
Use of SIT was associated with both disease severity measures and educational level, but not income level. These results suggest social inequality as reflected by lower use of SIT among patients with lower educational level may represent an obstacle to treatment with SIT.
目前对于接受变应原特异性免疫治疗患者的特征知之甚少。根据指南确定适当治疗的障碍,可能有助于制定旨在改善变应性呼吸道疾病患者治疗的策略。本研究的目的是调查接受变应原特异性免疫治疗和未接受变应原特异性免疫治疗的变应性鼻炎患者在疾病严重程度、人口统计学和社会经济状况方面的差异。
共研究了 366 名患者,其中 210 名患者将接受皮下免疫治疗(SIT)治疗草花粉和/或屋尘螨过敏。鼻结膜炎(花粉症)和/或哮喘的严重程度根据国际指南进行分类。调查问卷包括 EQ-5D 视觉模拟量表和一些社会经济问题。
疾病严重程度、年龄较小、教育程度较高以及因过敏症状对健康相关生活质量的感知损害较大,与 SIT 的使用显著相关。有点出人意料的是,家庭收入与 SIT 的使用无关。
SIT 的使用与疾病严重程度和教育程度有关,但与收入水平无关。这些结果表明,社会不平等反映在教育程度较低的患者中 SIT 的使用较低,这可能是 SIT 治疗的障碍。