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颅内脑脓肿继发于眼眶蜂窝织炎和鼻窦炎。

Intracranial brain abscess preceded by orbital cellulitis and sinusitis.

作者信息

Yeh Chung-Hsin, Chen Wen-Chao, Lin Maggie S F, Huang Hua-Tzu, Chao Shih-Chun, Lo Yi-Chen

机构信息

Department of Neurology, Show Chwan Memorial Hospital, Changhua, Taiwan.

出版信息

J Craniofac Surg. 2010 May;21(3):934-6. doi: 10.1097/SCS.0b013e3181d84124.

Abstract

A 17-year-old boy with pyrexia, headache, and frequent drop attacks reported an acute onset of periorbital pain and swelling 1 month previously. Coronal computed tomography (CT) identified an ethmoid sinusitis, which was treated with functional endoscopic sinus surgery and intravenous gentamicin, prostaphylline, and metronidazone. Because of persistent symptoms, the patient returned 1 month later. The CT identified accumulation of debris in both frontal sinuses and a multilobulated lesion over the right frontal lobe. Bicoronal craniotomy was performed, and a mass located in the right frontal lobe was excised; the mass comprised chronic inflammatory tissues without evidence of malignancy. A postoperative brain CT confirmed the absence of a residual mass, and no recurrence or neurologic deficits were noted during the 3-month follow-up period. Intracranial complications cannot be prevented entirely even with the judicious use of antibiotics. Early application of the appropriate imaging modality and institution of aggressive therapy in any patient, not just pediatric patients, to prevent potential long-term disabilities and death are essential.

摘要

一名17岁男孩,伴有发热、头痛及频繁跌倒发作,1个月前急性起病,出现眶周疼痛和肿胀。冠状位计算机断层扫描(CT)显示筛窦炎,接受了功能性鼻内镜鼻窦手术及静脉注射庆大霉素、前列腺素和甲硝唑治疗。因症状持续,患者1个月后复诊。CT显示双侧额窦有碎屑积聚,右侧额叶有一个分叶状病变。实施了双冠状开颅手术,切除了位于右侧额叶的一个肿块;该肿块由慢性炎症组织构成,无恶性证据。术后脑部CT证实无残留肿块,在3个月的随访期内未发现复发或神经功能缺损。即使合理使用抗生素,颅内并发症也无法完全预防。对任何患者,而非仅儿科患者,早期应用适当的影像学检查方法并采取积极治疗措施,以预防潜在的长期残疾和死亡至关重要。

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