Chen Kuan-Pin, Chou Yu-Cheng, Lee Chia-Fone, Harnod Tomor, Chen Shin-Yuan, Su Chain-Fa, Chen Peir-Rong, Chou Tsung-Lang
Department of Neurosurgery, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan.
Department of Otorhinolaryngology, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan.
Tzu Chi Med J. 2016 Jan-Mar;28(1):24-26. doi: 10.1016/j.tcmj.2014.06.004. Epub 2014 Jul 30.
Intracranial invasion of paranasal sinusitis is an emergency condition that requires surgical and medical intervention in order to avoid further deterioration. We surveyed patients at the Buddhist Tzu Chi Hospital (Hualien, Taiwan) who had paranasal sinusitis with intracranial invasion. A total of 505 patients with paranasal sinusitis were surveyed at Hualien Buddhist Tzu Chi Hospital over a 14-year period (2000-2013). Data on clinical presentations, microbiology, host factors, postinterventional morbidity, and postinterventional mortality are presented. Of the 505 patients, nine had intracranial invasions (incidence rate, 1.8%). The mortality rate was high among these patients (44.4%, 4/9). Among the various risk factors identified, diabetes had the greatest influence (66.7%, 6/9), which in combination with an immunocompromised condition and cirrhosis is indicative of a poor prognosis.
鼻窦炎性颅内侵犯是一种紧急情况，需要进行手术和药物干预以避免病情进一步恶化。我们对台湾花莲慈济医院患有鼻窦炎性颅内侵犯的患者进行了调查。在14年期间（2000 - 2013年），花莲慈济医院共对505例鼻窦炎患者进行了调查。本文呈现了关于临床表现、微生物学、宿主因素、介入治疗后发病率和介入治疗后死亡率的数据。在这505例患者中，有9例发生了颅内侵犯（发病率为1.8%）。这些患者的死亡率很高（44.4%，4/9）。在已确定的各种危险因素中，糖尿病的影响最大（66.7%，6/9），糖尿病与免疫功能低下及肝硬化共同作用预示着预后不良。
