Li Hongdi, Wang Chao, Baghaei Hossain, Zhang Yuxuan, Ramirez Rocio, Liu Shitao, An Shaohui, Wong Wai-Hoi
Department of Experimental Diagnostic Imaging, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030 USA.
IEEE Trans Nucl Sci. 2010 Apr;57(2):550-555. doi: 10.1109/TNS.2009.2036914.
The goal of this work is to develop a novel, accurate, real-time digital baseline restorer using online statistical processing for a high count-rate digital system such as positron emission tomography (PET). In high count-rate nuclear instrumentation applications, analog signals are DC-coupled for better performance. However, the detectors, pre-amplifiers and other front-end electronics would cause a signal baseline drift in a DC-coupling system, which will degrade the performance of energy resolution and positioning accuracy. Event pileups normally exist in a high-count rate system and the baseline drift will create errors in the event pileup-correction. Hence, a baseline restorer (BLR) is required in a high count-rate system to remove the DC drift ahead of the pileup correction. Many methods have been reported for BLR from classic analog methods to digital filter solutions. However a single channel BLR with analog method can only work under 500 kcps count-rate, and normally an analog front-end application-specific integrated circuits (ASIC) is required for the application involved hundreds BLR such as a PET camera. We have developed a simple statistics-based online baseline restorer (SOBLR) for a high count-rate fully digital system. In this method, we acquire additional samples, excluding the real gamma pulses, from the existing free-running ADC in the digital system, and perform online statistical processing to generate a baseline value. This baseline value will be subtracted from the digitized waveform to retrieve its original pulse with zero-baseline drift. This method can self-track the baseline without a micro-controller involved. The circuit consists of two digital counter/timers, one comparator, one register and one subtraction unit. Simulation shows a single channel works at 30 Mcps count-rate with pileup condition. 336 baseline restorer circuits have been implemented into 12 field-programmable-gate-arrays (FPGA) for our new fully digital PET system.
这项工作的目标是为正电子发射断层扫描(PET)等高计数率数字系统开发一种新颖、准确的实时数字基线恢复器,该恢复器采用在线统计处理。在高计数率核仪器应用中,模拟信号采用直流耦合以获得更好的性能。然而,探测器、前置放大器和其他前端电子设备会在直流耦合系统中导致信号基线漂移,这将降低能量分辨率和定位精度的性能。事件堆积通常存在于高计数率系统中,基线漂移会在事件堆积校正中产生误差。因此,在高计数率系统中需要一个基线恢复器(BLR)来在堆积校正之前消除直流漂移。从经典模拟方法到数字滤波器解决方案,已经报道了许多用于BLR的方法。然而,采用模拟方法的单通道BLR只能在500 kcps计数率下工作,对于涉及数百个BLR的应用(如PET相机),通常需要一个模拟前端专用集成电路(ASIC)。我们为高计数率全数字系统开发了一种基于简单统计的在线基线恢复器(SOBLR)。在这种方法中,我们从数字系统中现有的自由运行ADC获取额外的样本(不包括真实的伽马脉冲),并进行在线统计处理以生成基线值。该基线值将从数字化波形中减去,以恢复其零基线漂移的原始脉冲。这种方法无需微控制器即可自动跟踪基线。该电路由两个数字计数器/定时器、一个比较器、一个寄存器和一个减法单元组成。仿真表明,单通道在存在堆积情况时可在30 Mcps计数率下工作。我们已将336个基线恢复器电路集成到12个现场可编程门阵列(FPGA)中,用于我们新的全数字PET系统。