Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Gut Liver. 2008 Dec;2(3):193-8. doi: 10.5009/gnl.2008.2.3.193. Epub 2008 Dec 31.
BACKGROUND/AIMS: The incidence of Barrett's cancer is increasing in Western countries, but there have been only a few case reports of this condition in Korea. The aim of this study was to elucidate the endoscopic and pathologic characteristics of Barrett's cancer in a single center in Korea.
We retrospectively reviewed the demographic, endoscopic, and pathologic characteristics of six patients with Barrett's cancer, defined as a tumor centered above the esophagogastric junction and surrounded by Barrett's esophagus.
All six patients were male, and three (50%) were symptomatic. Barrett's cancer had developed from short-segment Barrett's esophagus in all patients. All tumors were located on the right side of the lower esophagus and showed hyperemic mucosal changes. Three patients were treated surgically and three by endoscopic resection. All cases had pathologic evidence of Barrett's cancer.
Early detection of Barrett's cancer requires meticulous endoscopic observations of subtle mucosal color and morphological changes around the esophagogastric junction.
背景/目的:西方国家 Barrett 食管癌的发病率正在上升,但在韩国,仅有少数几例该病的报告。本研究的目的是阐明韩国某单一中心 Barrett 食管癌的内镜和病理特征。
我们回顾性分析了 6 例 Barrett 食管癌患者的人口统计学、内镜和病理特征,这些患者的定义为肿瘤位于食管胃交界处上方,周围有 Barrett 食管。
所有 6 例患者均为男性,其中 3 例(50%)有症状。所有患者的 Barrett 食管癌均源自短节段 Barrett 食管。所有肿瘤均位于食管下段右侧,表现为充血性黏膜改变。3 例患者接受了手术治疗,3 例患者接受了内镜下切除。所有病例均有 Barrett 食管癌的病理证据。
要早期发现 Barrett 食管癌,需要对食管胃交界处周围的细微黏膜颜色和形态变化进行仔细的内镜观察。