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[马达加斯加肝硬化患者样本中的死亡原因]

[Causes of death in a sample of cirrhotic patients from Madagascar].

作者信息

Razafimahefa S H, Rabenjanahary T H, Rakotoarivelo R A, Ramilitiana B, Ramanampamonjy R M, Rajaona H R

机构信息

Service de gastroentérologie, hôpital Joseph Raseta Befelatanana, Centre hospitalier universitaire, Antananarivo, Madagascar.

出版信息

Med Trop (Mars). 2010 Apr;70(2):163-5.

PMID:20486353
Abstract

OBJECTIVE

Cirrhotic patients have poorer life expectancy than the general population. The purpose of this study was to identify causes of death in a sample of cirrhotic patients from Madagascar.

METHODS

A retrospective analytic and descriptive study was conducted on the files of cirrhotic inpatients admitted to the gastroenterology department of the Joseph Raseta Befelatanana University Hospital Center in Antananarivo, Madagascar from January 1, 2003 to June 30, 2007.

RESULTS

The files of 117 patients were reviewed. Death occurred in 31 cases for a mortality rate of 26.5%. The main causes of death were disorders of consciousness (51.6%) and hypovolemic shock (25.8%). Jaundice, encephalopathy, and gastrointestinal bleeding were predictive factors for mortality.

CONCLUSION

Cirrhotic patients in this study were hospitalized at a late stage of disease. Further prospective study in a larger sample will be needed to standardize the management protocol in Madagascar.

摘要

目的

肝硬化患者的预期寿命低于普通人群。本研究旨在确定马达加斯加肝硬化患者样本中的死亡原因。

方法

对2003年1月1日至2007年6月30日期间在马达加斯加塔那那利佛约瑟夫·拉塞塔·贝费拉塔纳纳大学医院中心胃肠病科住院的肝硬化患者病历进行回顾性分析和描述性研究。

结果

回顾了117例患者的病历。31例死亡,死亡率为26.5%。主要死亡原因是意识障碍(51.6%)和低血容量性休克(25.8%)。黄疸、肝性脑病和胃肠道出血是死亡的预测因素。

结论

本研究中的肝硬化患者在疾病晚期住院。需要在更大样本中进行进一步的前瞻性研究,以规范马达加斯加的管理方案。

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引用本文的文献

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Factors Associated with in-Hospital Mortality in Malagasy Patients with Acute Decompensation of Liver Cirrhosis: A Retrospective Cohort.马达加斯加肝硬化急性失代偿患者院内死亡的相关因素:一项回顾性队列研究
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