School of Nursing, University of Botswana, Gaborone, Botswana.
Int Nurs Rev. 2010 Mar;57(1):142-4. doi: 10.1111/j.1466-7657.2009.00743.x.
The aim of this short communication is to share my personal experience of caring for a terminally ill family member who was afflicted with Pick's disease. I tell my story in the hope of increasing society's awareness on this little known but devastating disease and assisting those who might be facing a similar situation. Pick's disease is a rare and incurable type of dementia that is associated with atrophy of the frontal and temporal lobes of the brain over time as a result of accumulation of tau protein fibres known as Pick's bodies. The exact cause is not known, but genetic predisposition is implicated in some disease cases. Pick's disease tends to affect men and women alike. It affects thinking, language and problem solving.
Data supporting this document were obtained from a thorough review of the literature and Internet search on Pick's disease, as well as from a personal experience with Pick's disease as it was unfolding.
Clinical features, diagnosis and treatment, and stages of the disease are presented.
Very little is known about Pick's disease. Additional research is needed to inform practice about tau protein dementias.
本短文旨在分享我个人照顾患有皮克氏病的绝症亲属的经历。我讲述自己的故事，是希望提高社会对这种鲜为人知但却极具破坏性的疾病的认识，并帮助那些可能面临类似情况的人。皮克氏病是一种罕见且无法治愈的痴呆症，随着时间的推移，由于tau 蛋白纤维（称为 Pick 体）的积累，大脑额颞叶会逐渐萎缩。确切的病因尚不清楚，但一些病例与遗传易感性有关。皮克氏病倾向于影响男性和女性。它会影响思维、语言和解决问题的能力。
本文的数据来源于对皮克氏病的文献综述和互联网搜索，以及对皮克氏病的个人体验。
呈现了该病的临床特征、诊断和治疗以及疾病的阶段。
人们对皮克氏病知之甚少。需要开展更多的研究，以便为 tau 蛋白痴呆症的治疗提供信息。
