与亲人一起经历皮克病之旅：个人叙述。

The journey through Pick's Disease with a loved one: a personal account.

机构信息

School of Nursing, University of Botswana, Gaborone, Botswana.

出版信息

Int Nurs Rev. 2010 Mar;57(1):142-4. doi: 10.1111/j.1466-7657.2009.00743.x.

DOI:10.1111/j.1466-7657.2009.00743.x

PMID:20487487

Abstract

BACKGROUND

The aim of this short communication is to share my personal experience of caring for a terminally ill family member who was afflicted with Pick's disease. I tell my story in the hope of increasing society's awareness on this little known but devastating disease and assisting those who might be facing a similar situation. Pick's disease is a rare and incurable type of dementia that is associated with atrophy of the frontal and temporal lobes of the brain over time as a result of accumulation of tau protein fibres known as Pick's bodies. The exact cause is not known, but genetic predisposition is implicated in some disease cases. Pick's disease tends to affect men and women alike. It affects thinking, language and problem solving.

METHODS

Data supporting this document were obtained from a thorough review of the literature and Internet search on Pick's disease, as well as from a personal experience with Pick's disease as it was unfolding.

RESULTS

Clinical features, diagnosis and treatment, and stages of the disease are presented.

CONCLUSION

Very little is known about Pick's disease. Additional research is needed to inform practice about tau protein dementias.

摘要

背景

本短文旨在分享我个人照顾患有皮克氏病的绝症亲属的经历。我讲述自己的故事，是希望提高社会对这种鲜为人知但却极具破坏性的疾病的认识，并帮助那些可能面临类似情况的人。皮克氏病是一种罕见且无法治愈的痴呆症，随着时间的推移，由于tau 蛋白纤维（称为 Pick 体）的积累，大脑额颞叶会逐渐萎缩。确切的病因尚不清楚，但一些病例与遗传易感性有关。皮克氏病倾向于影响男性和女性。它会影响思维、语言和解决问题的能力。