Hanwell M A, Cooper N A, Kidman A D
Neurobiology Unit, School of Life Sciences, New South Wales Institute of Technology, Dunbar Building, Wesbourne Street, Gore Hill, N.S.W. 2065 Australia.
Neurochem Int. 1982;4(6):467-71. doi: 10.1016/0197-0186(82)90035-3.
Remyelination in the chicken sciatic nerve occurring after the injection of diphtheria toxin was studied. The rates of fast axonal transport and conduction velocities were measured sixty days after the injection of the toxin. Fast axonal transport rates were found to have returned to normal in the remyelinated nerves, but conduction velocity was markedly reduced even though the birds appeared to walk normally. The remyelinated nerve fibres had on histological examination relatively thin myelin sheaths. Of greater interest was the number of Schmidt-Lanterman clefts observed in both the control and remyelinated nerves when viewed in the electron microscope.
研究了注射白喉毒素后鸡坐骨神经的髓鞘再生情况。在注射毒素60天后测量了快速轴突运输速率和传导速度。发现再生髓鞘神经的快速轴突运输速率已恢复正常，但尽管鸡看起来行走正常，其传导速度却显著降低。经组织学检查，再生髓鞘的神经纤维具有相对较薄的髓鞘。更有趣的是，在电子显微镜下观察时，对照神经和再生髓鞘神经中观察到的施密特-兰特尔曼切迹的数量。
