Hines D W, Haber M H, Yaremko L, Britton C, McLawhon R W, Harris A A
Department of Medicine and Pathology, Rush Presbyterian-St. Luke's Hospital, Chicago, Illinois.
Am Rev Respir Dis. 1991 Jun;143(6):1408-11. doi: 10.1164/ajrccm/143.6.1408.
Four immunosuppressed patients with a rapidly evolving, febrile, respiratory distress syndrome were found at autopsy to have Aspergillus pseudomembranes of their lower tracheobronchial tree. Steroids, neutropenia, broad spectrum antibiotic use, and alcoholism appear to be predisposing risk factors. Bronchoscopy may reveal the pathology but antemortem diagnosis is difficult because of the low yield of sputum cultures and fulminant nature of the disease.
对4例患有快速进展的发热性呼吸窘迫综合征的免疫抑制患者进行尸检时发现,其下气管支气管树存在曲霉假膜。类固醇、中性粒细胞减少、使用广谱抗生素和酗酒似乎是诱发风险因素。支气管镜检查可能会发现病变,但由于痰培养阳性率低以及疾病的暴发性,生前诊断很困难。