Pettersson Jonas, Wagner Galen S, Sörnmo Leif, Johansson Elin Trägårdh, Ohlin Hans, Pahlm Olle
Department of Clinical Physiology, Lund University, Lund, Sweden.
J Electrocardiol. 2011 Jan-Feb;44(1):11-7. doi: 10.1016/j.jelectrocard.2010.04.006. Epub 2010 May 21.
Resolution of ST-segment elevation in the electrocardiogram (ECG) is used as a reperfusion sign during thrombolytic therapy in acute myocardial infarction. Analysis of high-frequency QRS components (HF-QRS) might provide additional information. The study compares changes in HF-QRS (150-250 Hz) to ST-segment changes in the standard ECG during thrombolytic therapy.
Twelve patients receiving intravenous thrombolytic therapy were included. A continuous 12-lead ECG recording was acquired for 4 hours.
After 1 hour of therapy, 3 patients showed ST-elevation resolution as well as an increase in HF-QRS. These changes in ST and HF-QRS occurred simultaneously. No other patient showed significant changes in ST or HF-QRS after 1 hour. After 2 and 4 hours, there was less concordance between the standard and high-frequency ECGs.
In patients with early ST-elevation resolution, the standard and high-frequency ECGs show similar results. Later changes are more disparate and may provide different clinical information.
在急性心肌梗死的溶栓治疗中，心电图（ECG）上ST段抬高的消退被用作再灌注的标志。高频QRS成分（HF-QRS）分析可能会提供更多信息。本研究比较了溶栓治疗期间HF-QRS（150-250Hz）的变化与标准ECG中ST段的变化。
纳入12例接受静脉溶栓治疗的患者。连续记录12导联ECG 4小时。
治疗1小时后，3例患者ST段抬高消退，同时HF-QRS增加。ST段和HF-QRS的这些变化同时发生。1小时后，其他患者的ST段或HF-QRS均未出现明显变化。2小时和4小时后，标准ECG与高频ECG之间的一致性降低。
在早期ST段抬高消退的患者中，标准ECG和高频ECG显示出相似的结果。后期变化差异更大，可能提供不同的临床信息。
