Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Kangnam-gu, Seoul, Korea.
AJR Am J Roentgenol. 2010 Jun;194(6):1461-9. doi: 10.2214/AJR.09.3654.
The objective of this article is to review the basic concepts for the biologic basis of diffusion-weighted MRI (DWI), illustrate its potential clinical applications at 3 T, and discuss its current limitations and future directions.
The increased signal-to-noise ratio of DWI provided by 3 T compared with 1.5 T may improve tumor detection and staging, determination of tumor aggressiveness, and posttreatment follow-up. Additionally, DWI may be a useful tool to monitor therapeutic effects and guide targeted biopsies, particularly in patients with previously negative biopsy results.
本文旨在回顾扩散加权磁共振成像（DWI）的生物学基础的基本概念，阐述其在 3T 场强下的潜在临床应用，并讨论其目前的局限性和未来方向。
与 1.5T 相比，3T 提供的 DWI 信号噪声比增加，可能会提高肿瘤的检出和分期、肿瘤侵袭性的判断以及治疗后的随访。此外，DWI 可能是一种有用的工具，可用于监测治疗效果并指导靶向活检，特别是在先前活检结果阴性的患者中。
