Li Yan, Zhang Zhiguang, Wu Shuyi, Qiao Yonggang
Department of Prosthodontics, Hospital of Stomatology, Guanghua College of Stomatology, Sun Yat-sen University, Guangzhou, China.
J Craniofac Surg. 2010 Mar;21(2):450-7. doi: 10.1097/SCS.0b013e3181cfe986.
This study aimed to establish a rat model of increasing occlusal vertical dimension (iOVD) using a prosthodontic approach. The OVD was increased by bonding a maxillary, bilateral, posterior dental splint with a bearing ball while the occlusal stops that were made on the stone casts adjusted the occlusion and bonded in the mouths of adult Wistar rats (iOVD group); the controls did not receive a splint. Both groups were subdivided after splint insertion: 3 days and 1, 2, 3, or 4 weeks (n = 6/subgroup). The effects of iOVD were evaluated by radiographs, body weight, and histologic diagnosis of tooth and temporomandibular joints. There were no differences in body weights between the 2 groups; occlusal asymmetric dentition abrasions did not occur in the iOVD rats. The occlusal splints caused the remodeling of the periodontal tissue and condylar cartilage. Overall, an iOVD rat model can be constructed using prosthodontic techniques ensuring a balance of bilateral occlusal height.
OVD, occlusal vertical dimension; iOVD, increasing occlusal vertical dimension; TMJ, temporomandibular joint; TMD, temporomandibular disorders.
本研究旨在采用口腔修复学方法建立大鼠咬合垂直距离增加（iOVD）模型。通过在成年Wistar大鼠口腔内粘结带有支撑球的上颌双侧后牙夹板来增加咬合垂直距离，同时在石膏模型上制作咬合止点以调整咬合并粘结（iOVD组）；对照组不佩戴夹板。夹板植入后两组均再分为：3天以及1、2、3或4周（每组n = 6）。通过X线片、体重以及牙齿和颞下颌关节的组织学诊断来评估iOVD的影响。两组体重无差异；iOVD大鼠未出现咬合不对称性牙列磨损。咬合夹板导致牙周组织和髁突软骨发生重塑。总体而言，可采用口腔修复技术构建iOVD大鼠模型，确保双侧咬合高度平衡。
OVD，咬合垂直距离；iOVD，咬合垂直距离增加；TMJ，颞下颌关节；TMD，颞下颌关节紊乱病
