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同种异体骨与钛笼在胸腰椎椎体置换中的比较:一项生物力学研究。

Comparison of allograft bone and titanium cages for vertebral body replacement in the thoracolumbar spine: a biomechanical study.

机构信息

Department of Neurosurgery, Louisiana State University Health Sciences Center-Shreveport, Shreveport, Louisiana 71130-3932, USA.

出版信息

Neurosurgery. 2010 Jun;66(6 Suppl Operative):314-8; discussion 318. doi: 10.1227/01.NEU.0000370200.74098.CC.

Abstract

BACKGROUND

When an anterior approach to repair a burst fracture is indicated, several devices can be used to restore spinal stability (eg, bone graft, free-standing titanium cage, and expandable titanium cage).

OBJECTIVE

We compare the biomechanical stability and prices of each of these systems.

MATERIALS AND METHODS

Eight fresh human cadaver T11 through L3 vertebral specimens were harvested and cleaned of soft tissues. T11-T12 and L2-L3 were fixed by screws. The fixed ends were then set in automotive body filler (Bondo). The prepared specimens were tested in the Biaxial Instron tester (8874, Norwood, MA) after a sequence of the following: intact, after the creation of an anterior corpectomy at L1, and after insertion of both of the 2 different titanium cages and the fibular graft. A titanium screw-and-plate anterolateral system was used to secure the construct (VANTAGE, Medtronic Sofamor Danek, Memphis, TN). The conditions of displacement testing were as follows: rotation (+/- 3.5 degrees ), flexion and extension, and left and right bending (+/- 3.5 mm). For each mode of testing, the stiffness was calculated.

RESULTS

The stiffness data, when statistically analyzed by repeated-measures analysis of variance (at P = .05 and power > 0.9), indicated no significant differences among these devices.

CONCLUSION

On the basis of this biomechanical study, the stiffness of the fibular graft was similar to that of the other metallic devices in this cadaver model.

摘要

背景

当需要采用前路入路修复爆裂性骨折时,可以使用几种不同的器械来恢复脊柱稳定性(例如骨移植物、独立式钛笼和可扩张钛笼)。

目的

我们比较了这些系统的每个系统的生物力学稳定性和价格。

材料和方法

从 8 具新鲜的人体 T11 至 L3 脊柱标本中取出并清除软组织。T11-T12 和 L2-L3 通过螺钉固定。然后将固定端设置在汽车车身填充物(Bondo)中。在以下顺序对准备好的标本进行测试:完整的标本,在 L1 处进行前路椎体切除术之后的标本,以及在插入两种不同的钛笼和腓骨移植物之后的标本。使用钛螺钉和板前路系统(VANTAGE,Medtronic Sofamor Danek,孟菲斯,田纳西州)来固定构建体。位移测试的条件如下:旋转(±3.5 度),屈伸和左右弯曲(±3.5 毫米)。对于每种测试模式,都计算了刚度。

结果

通过重复测量方差分析(在 P =.05 且功率> 0.9 时)对刚度数据进行统计学分析,结果表明这些器械之间没有显著差异。

结论

根据这项生物力学研究,在这个尸体模型中,腓骨移植物的刚度与其他金属器械相似。

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