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甲状腺髓样癌伴微小肺转移:一例报告并着重于影像学表现

Medullary thyroid carcinoma with micronodular lung metastases: a case report with an emphasis on the imaging findings.

作者信息

Ventura Nina, Marchiori Edson, Zanetti Gláucia, Muccillo Antonio, Pereira Mariana Leite, Abdalla Guilherme, Martins Pedro, Constantino Carolina Lamas, Canellas Rodrigo, Brandão Viviane, Varella de Oliveira Romulo

机构信息

Department of Radiology, Rio de Janeiro Federal University, Rio de Janeiro, CEP 21941.913, Brazil.

出版信息

Case Rep Med. 2010;2010:616580. doi: 10.1155/2010/616580. Epub 2010 May 17.

DOI:10.1155/2010/616580
PMID:20490356
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2872764/
Abstract

Medullary thyroid carcinoma is a rare malignancy that arises from calcitonin-producing C-cells and frequently metastasizes to lymph nodes in the neck. Distant metastases may involve bone, lung, and liver. The infrequent number of cases limits the clinical nature and ability to optimize diagnostic tools. Here, we present a case of a micronodular radiographic pattern in metastatic medullary thyroid cancer in order to enhance awareness of the disease process. A case discussion and relevant review of the literature are provided.

摘要

甲状腺髓样癌是一种罕见的恶性肿瘤,起源于产生降钙素的C细胞,常转移至颈部淋巴结。远处转移可能累及骨骼、肺和肝脏。病例数量较少限制了其临床特征以及优化诊断工具的能力。在此,我们报告一例转移性甲状腺髓样癌的微结节影像学表现病例,以提高对该疾病过程的认识。并提供了病例讨论及相关文献综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e627/2872764/e0ebbc536e80/CRM2010-616580.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e627/2872764/52bdcf9e25ba/CRM2010-616580.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e627/2872764/e0ebbc536e80/CRM2010-616580.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e627/2872764/52bdcf9e25ba/CRM2010-616580.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e627/2872764/e0ebbc536e80/CRM2010-616580.002.jpg

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本文引用的文献

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Medullary thyroid carcinoma with poor differentiation and atypical radiographic pattern of metastasis.
Pathol Int. 2009 Sep;59(9):660-3. doi: 10.1111/j.1440-1827.2009.02423.x.
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Comparison of (68)Ga-DOTATATE and (18)F-fluorodeoxyglucose PET/CT in the detection of recurrent medullary thyroid carcinoma.比较 (68)Ga-DOTATATE 和 (18)F-氟脱氧葡萄糖 PET/CT 在检测复发性甲状腺髓样癌中的应用。
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Medullary thyroid carcinoma metastatic to skin.转移性至皮肤的甲状腺髓样癌。
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J Cutan Pathol. 2010 Dec;37(12):1237-40. doi: 10.1111/j.1600-0560.2009.01365.x.
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Imaging medullary thyroid carcinoma with persistent elevated calcitonin levels.对降钙素水平持续升高的甲状腺髓样癌进行成像。
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Micronodular radiographic pulmonary pattern in metastatic medullary thyroid carcinoma.甲状腺髓样癌转移的肺部微结节影像学表现
J Natl Med Assoc. 2007 May;99(5):575-7.
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Int Surg. 2006 May-Jun;91(3):162-7.
10
Survival improvement in patients with medullary thyroid carcinoma who undergo pretargeted anti-carcinoembryonic-antigen radioimmunotherapy: a collaborative study with the French Endocrine Tumor Group.接受预靶向抗癌胚抗原放射免疫治疗的甲状腺髓样癌患者的生存改善:与法国内分泌肿瘤研究组的合作研究
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